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2.A.1.4.2
P-glycerate:Pi antiporter, Pgt.  Takes up phosphoenolpyruvate, 2-phosphoglycerate, and 3-phosphoglycerate as sole sources of carbon and energy for rapid growth (Saier et al. 1975).  Not present in E. coli K12, but is present in many intracellular pathogenic strains of E. coli (Tang and Saier, unpublished observations).

Accession Number:P12681
Protein Name:PgtP aka STM2399
Length:463
Molecular Weight:50999.00
Species:Salmonella typhimurium [90371]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate phosphoglycerates, phosphate

Cross database links:

HEGENOM: HBG559184
RefSeq: NP_461340.1   
Entrez Gene ID: 1253921   
Pfam: PF07690   
BioCyc: STYP99287:STM2399-MONOMER   
KEGG: stm:STM2399   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (2)

[1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609
[2] “Nucleotide sequence and transcription start point of the phosphoglycerate transporter gene of Salmonella typhimurium.”  Goldrick D.et.al.   3042749

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLTILKTGQS AHKVPPEKVQ ATYGRYRIQA LLSVFLGYLA YYIVRNNFTL STPYLKEQLD 
61:	LSATQIGLLS SCMLIAYGIS KGVMSSLADK ASPKVFMACG LVLCAIVNVG LGFSSAFWIF 
121:	AALVVFNGLF QGMGVGPSFI TIANWFPRRE RGRVGAFWNI SHNVGGGIVA PIVGAAFAIL 
181:	GSEHWQSASY IVPACVAVIF ALIVLVLGKG SPRKEGLPSL EQMMPEEKVV LKTKNTAKAP 
241:	ENMSAWQIFC TYVLRNKNAW YISLVDVFVY MVRFGMISWL PIYLLTVKHF SKEQMSVAFL 
301:	FFEWAAIPST LLAGWLSDKL FKGRRMPLAM ICMALIFVCL IGYWKSESLL MVTIFAAIVG 
361:	CLIYVPQFLA SVQTMEIVPS FAVGSAVGLR GFMSYIFGAS LGTSLFGVMV DKLGWYGGFY 
421:	LLMGGIVCCI LFCYLSHRGA LELERQRQNA LHNQDSLQLA DAQ