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2.A.1.4.7
Putative glycerol-3-phosphate (G-3-P) transporter, G3PP (most similar to TC# 2.A.1.4.6, 22% identity).  Has been shown to catalyze glucose 6-P:Pi antiport across the endoplasmic reticular membrane(Pan et al. 2011).

Accession Number:P57057
Protein Name:Glycerol-3-phosphate transporter aka G3PP
Length:533
Molecular Weight:57662.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Glycerol-3-phosphate, Glucose-6-phosphate, phosphate

Cross database links:

Genevestigator: P57057 P57057
eggNOG: prNOG15161 COG2271
HEGENOM: HBG384033 HOG000230522
RefSeq: NP_061837.3   
Entrez Gene ID: 54020   
Pfam: PF07690   
OMIM: 608094  gene
KEGG: hsa:54020    hsa:54020   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008643 P:carbohydrate transport
GO:0055085 P:transmembrane transport
GO:0005215 F:transporter activity

References (3)

[1] “Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency.”  Bartoloni L.et.al.   11112347
[2] “Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency.”  Bartoloni L.et.al.   11112347
[3] “The DNA sequence of human chromosome 21.”  Hattori M.et.al.   10830953

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MARLPAGIRF IISFSRDQWY RAFIFILTFL LYASFHLSRK PISIVKGELH KYCTAWDEAD 
61:	VRFSSQNRKS GSAAPHQLPD NETDCGWAPF DKNNYQQLLG ALDYSFLCAY AVGMYLSGII 
121:	GERLPIRYYL TFGMLASGAF TALFGLGYFY NIHSFGFYVV TQVINGLVQT TGWPSVVTCL 
181:	GNWFGKGRRG LIMGVWNSHT SVGNILGSLI AGYWVSTCWG LSFVVPGAIV AAMGIVCFLF 
241:	LIEHPNDVRC SSTLVTHSKG YENGTNRLRL QKQILKSEKN KPLDPEMQCL LLSDGKGSIH 
301:	PNHVVILPGD GGSGTAAISF TGALKIPGVI EFSLCLLFAK LVSYTFLFWL PLYITNVDHL 
361:	DAKKAGELST LFDVGGIFGG ILAGVISDRL EKRASTCGLM LLLAAPTLYI FSTISKMGLE 
421:	ATIAMLLLSG ALVSGPYTLI TTAVSADLGT HKSLKGNAHA LSTVTAIIDG TGSVGAALGP 
481:	LLAGLLSPSG WSNVFYMLMF ADACALLFLI RLIHKELSCP GSATGDQVPF KEQ