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2.A.1.4.8
solute carrier family 37 (putative glycerol-3-phosphate transporter), member 2.  Has been shown to catalyze glucose 6-P:Pi antiport across the endoplasmic reticular membrane (Pan et al. 2011).

Accession Number:Q8TED4
Protein Name:Sugar phosphate exchanger 2
Length:501
Molecular Weight:54436.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Glycerol-3-phosphate

Cross database links:

Genevestigator: Q8TED4 Q8TED4
eggNOG: COG2271 COG2271
HEGENOM: HOG000230522 HOG000230522
Entrez Gene ID: 219855   
Pfam: PF07690   
KEGG: hsa:219855    hsa:219855   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0008643 P:carbohydrate transport
GO:0055085 P:transmembrane transport

References (6)

[1] “Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.”  Jikuya H.et.al.   12693554
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.”  Jikuya H.et.al.   12693554
[5] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRSSLAPGVW FFRAFSRDSW FRGLILLLTF LIYACYHMSR KPISIVKSRL HQNCSEQIKP 
61:	INDTHSLNDT MWCSWAPFDK DNYKELLGGV DNAFLIAYAI GMFISGVFGE RLPLRYYLSA 
121:	GMLLSGLFTS LFGLGYFWNI HELWYFVVIQ VCNGLVQTTG WPSVVTCVGN WFGKGKRGFI 
181:	MGIWNSHTSV GNILGSLIAG IWVNGQWGLS FIVPGIITAV MGVITFLFLI EHPEDVDCAP 
241:	PQHHGEPAEN QDNPEDPGNS PCSIRESGLE TVAKCSKGPC EEPAAISFFG ALRIPGVVEF 
301:	SLCLLFAKLV SYTFLYWLPL YIANVAHFSA KEAGDLSTLF DVGGIIGGIV AGLVSDYTNG 
361:	RATTCCVMLI LAAPMMFLYN YIGQDGIASS IVMLIICGGL VNGPYALITT AVSADLGTHK 
421:	SLKGNAKALS TVTAIIDGTG SIGAALGPLL AGLISPTGWN NVFYMLISAD VLACLLLCRL 
481:	VYKEILAWKV SLSRGSGYKE I