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2.A.1.47.3
Possible antibiotic peptide exporter (encoded in an operon together with lantibiotic biosynthesis enzymes)

Accession Number:B2IRN2
Protein Name:Lantibiotic efflux protein
Length:418
Molecular Weight:46491.00
Species:Streptococcus pneumoniae (strain CGSP14) [516950]
Number of TMSs:8
Substrate Unknown

Cross database links:

HEGENOM: HBG702972
Entrez Gene ID: 6217420   
Pfam: PF05977   
KEGG: spw:SPCG_0147   

References (1)

[1] “Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14.”  Ding F.et.al.   19361343

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKILNNKLY MKVLVSDLIS NFGDTLYFIA LMTYVTEIKS SNLAISIVNI SETIPILFTI 
61:	FFGIIADRTL NKVGMIIKTL WIRTILYLLV AVVMNFKESI LVVILASIVN LISDTLGQFE 
121:	NGLFYPISNR IVKKSDREET MAFRQTATST MNIVNQSLGA FLITFLSFFH LALINSLTFA 
181:	ISLLITLAIK SQINNFYIDK TPSTKVSKVD FKATFSDIIS NLKLSLKHLF SLTNMKTVLL 
241:	VIPILNGSLA IIIPLAVVNL SKSSALTIIS SATTISVLGI STVSGGILGG TLILISKKFK 
301:	NLSIENLLKM NLMTILLSFI AFYYQNIYFI VLTLFLSSVF VSALNPKIGA IIFNNLDETK 
361:	LATIFGGMVT YFQLGDVVSR LLFSTLVIYL SYTYIAVIYM ILVLIVAIYT FRRVQTTS