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2.A.1.57.1
The Ferripyochelin uptake permease, FptX (Michel et al., 2007).  Also transports N-acetylglucosamine anhydrous N-acetylmuramyl peptides and is called AmpP or AmpGh1 (Kong et al. 2010).  However, it does not play a role in the induction of β-lactam resistance (Zhang et al. 2010).

Accession Number:Q9HWG8
Protein Name:FptX
Length:414
Molecular Weight:43151.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Ferripyochelin, N-acetyglucosamine, Anhydrous N-acetylmuramyl peptides

Cross database links:

HEGENOM: HBG713261
RefSeq: NP_252908.1   
Entrez Gene ID: 880532   
Pfam: PF07690   
BioCyc: PAER208964:PA4218-MONOMER   
KEGG: pae:PA4218   

Gene Ontology

GO:0055085 P:transmembrane transport

References (1)

[1] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLELYRHRRL VITLALLYLS QGIPIGLAMD ALPTLLRQDG APLQALAFLP LVGLPWVVKF 
61:	LWAPWVDNHW SRRLGRRRSW ILPMQCMVLA CLLGLATLGL GVASAGWAVG LLALASLASA 
121:	TQDIATDGMA AEHFSGELLA KVNAVQIAGV MIGFFGGGAG SLILAGHFGQ RTAFLVMACV 
181:	PLASLCCVLA LGRGDPHELP PAPAAKASLL RFLRRPLAPS LLALALLSAM TAVSGFGLSK 
241:	LYLSDAGWAL QDIGRLGMSG GLVTVFLGCG GGAWLVRRIG LWRGFALGVV LAGCSALLWY 
301:	LQAGRWLALS EGLAWTCVLI GSLATGITSV AILTAAMRFA GQGGQAGTDV TAVQSTRDLG 
361:	EMLASSFLVS LTAQIGYAGG FLTGSALAVL ALLLALRLQA GEGRGEWKGR AEEA