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2.A.1.6.5
4-Methyl-o-phthalate:H+ symporter

Accession Number:Q45082
Protein Name:MopB
Length:449
Molecular Weight:48306.00
Species:Burkholderia cepacia (Pseudomonas cepacia) [292]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate H+, 4-methyl-o-phthalate

Cross database links:

Pfam: PF07690    PF00083   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “4-Methylphthalate catabolism in Burkholderia (Pseudomonas) cepacia Pc701: a gene encoding a phthalate-specific permease forms part of a novel gene cluster.”  Saint C.P.et.al.   8828207

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKAFETSQEW HGTVTSTESA SGANTTESGS RRLFFASFLG TMVEWYDFFL YGFIAPLVFE 
61:	ELFFPKLNAL SGTIAVYATF AVGYASRPLG GLVFGHFGDK IGRKSMMLVT LLMMGIGTAA 
121:	IGLLPSVAQI GMSATCLLVA LRFVQGFALG GESAAASLMV LESAQQRRRG LLGAALQAAG 
181:	PLGVLLASLA VFVVSRLPHD ALLAWGWRVP FLVSAVLVVI GLYIRLRVEE TVAFRKQQSK 
241:	HELTRIPAWE TLRSYKWPVF VVLVVSIMES TFYYLTGVYS ISYVTKTLHM PGSVAIGAIA 
301:	CANAFALVSV PLYGALSDRL GRKGVYLLGI VASAIYLNFF FTMLDGRSAM VVVLAVVAAV 
361:	GVIHAPMYAM FGSFYGELFP TRVRFTGFSM GKAFGTVLGG GIAPMIAASL AARNHGDPSA 
421:	IGLYYLCLAF VALCVVLRVR ETRNDDITV