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2.A.1.6.7
The citrate/tricarballylate:H+ symporter (CitA or TcuC); probably orthologous to 2.A.1.6.1 (Lewis et al., 2004)

Accession Number:P0A2G3
Protein Name:CitA
Length:434
Molecular Weight:47189.00
Species:Salmonella typhimurium [90371]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Tricarballylate, Citrate

Cross database links:

HEGENOM: HBG757988
RefSeq: NP_459674.1   
Entrez Gene ID: 1252209   
Pfam: PF00083   
BioCyc: STYP99287:STM0689-MONOMER   
KEGG: stm:STM0689   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015293 F:symporter activity
GO:0006101 P:citrate metabolic process
GO:0055085 P:transmembrane transport

References (2)

[1] “Cloning and nucleotide sequence of the gene (citA) encoding a citrate carrier from Salmonella typhimurium.”  Shimamoto T.et.al.   1718953
[2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAQHTPATSR AGTFGAILRV TSGNFLEQFD FFLFGFYATY IARTFFPAES EFASLMLTFA 
61:	VFGSGFLMRP VGAIVLGAYI DRIGRRKGLM VTLAIMGCGT LLIALVPGYQ TIGLAAPALV 
121:	LLGRLLQGFS AGVELGGVSV YLSEIATPGN KGFYTSWQSA SQQVAIVVAA LIGYSLNITL 
181:	GHDAISEWGW RIPFFIGCMI IPLIFVLRRS LQETEAFLQR KHRPDTREIF ATIAKNWRII 
241:	TAGTLLVAMT TTTFYFITVY TPTYGRTVLN LSARDSLIVT MLVGVSNFIW LPIGGAISDR 
301:	IGRRAVLMGI TLLALITTWP VMQWLTAAPD FTRMTLVLLW FSFFFGMYNG AMVAALTEVM 
361:	PVYVRTVGFS LAFSLATAIF GGLTPAISTA LVKLTGDKSS PGWWLMCAAL CGLAATAMLF 
421:	VRLSRGYIAA ENKA