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2.A.1.66.2
Putative 4-hydroxybenzoate uptake transporter, MFS_1 (in an operon with 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase of the methionine salvage pathway), using S-adenyl methionine (SAM) as substrate. May transport SAM.

Accession Number:Q8F7L4
Protein Name:Putative 4-hydroxybenzoate transporter transmembrane protein
Length:460
Molecular Weight:50729.00
Species:Leptospira interrogans [173]
Number of TMSs:12
Substrate 4-hydroxybenzoate, SAM

Cross database links:

Entrez Gene ID: 1150273   
Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0055085 P:transmembrane transport

References (1)

[1] “Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing.”  Ren S.-X.et.al.   12712204

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEKSPSDKSL LRFFGLGELV NHGWNAILAF WMIMGMAFFL FADQNLIAPN LKNIGASFGL 
61:	NNQEDVDWYI GGVIPILFFI LGGAVSVSMG YLSQKYSRKT LIIFSVFLGE VPCFLSGFAT 
121:	SYPEFVFYRT LTGFGLGGIF PLLFTVLGDY FSDKSRSTAA AYVSLSMGIG LGVGQLLGGI 
181:	LGSADPANGW RTSFIYLSIP SFFFAIIYWI FCKEPIRGGG ESEWSGIAEK FSEESFHLRW 
241:	NDVRLLFKNK TNIGIFLQGI PGCVPWGVFF VFLVDYYETS YHLDKATATM LLTYAAIGVF 
301:	AGTFFGGIIG QKIYNYKKRL LPIFCMSSIL IGILPCIYLL KAENIADSGL FILINVVAGF 
361:	IISVTGPNVR ATLINVNIPK NRSSMFALYN LTDDLGKGLG PAMSALILGL TPGDRSLGLS 
421:	ISVLFWIPCA LSWLIVLKNF EKDEKDVHEY LVLEAEKIKG