TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.7.14
Protein TsgA, also called GutS, YhfC, YhfH.  tsgA i(gutS) gene expression is up-regulated by tellurite and selenite (Guzzo and Dubow 2000).

Accession Number:P60778
Protein Name:Protein TsgA
Length:393
Molecular Weight:43166.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Unknown, NONE

Cross database links:

Genevestigator: P60778
EchoBASE: EB1242
EcoGene: EG11262
eggNOG: COG0477
HEGENOM: HOG000290517
Entrez Gene ID: 947869   
Pfam: PF07690   
KEGG: eco:b3364   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0055085 P:transmembrane transport

References (7)

[1] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[2] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[3] “Nucleotide sequences of fic and fic-1 genes involved in cell filamentation induced by cyclic AMP in Escherichia coli.”  Kawamukai M.et.al.   2546924
[4] “Cloning of binding sequences for the Escherichia coli transcription activators, FNR and CRP: location of bases involved in discrimination between FNR and CRP.”  Bell A.I.et.al.   2543955
[5] “Nucleotide sequence, organisation and structural analysis of the products of genes in the nirB-cysG region of the Escherichia coli K-12 chromosome.”  Peakman T.et.al.   2200672
[6] “A novel selenite- and tellurite-inducible gene in Escherichia coli.”  Guzzo J.et.al.   11055951
[7] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MTNSNRIKLT WISFLSYALT GALVIVTGMV MGNIADYFNL PVSSMSNTFT FLNAGILISI 
61:	FLNAWLMEIV PLKTQLRFGF LLMVLAVAGL MFSHSLALFS AAMFILGVVS GITMSIGTFL 
121:	VTQMYEGRQR GSRLLFTDSF FSMAGMIFPM IAAFLLARSI EWYWVYACIG LVYVAIFILT 
181:	FGCEFPALGK HAPKTDAPVE KEKWGIGVLF LSVAALCYIL GQLGFISWVP EYAKGLGMSL 
241:	NDAGTLVSNF WMSYMVGMWA FSFILRFFDL QRILTVLAGL AAILMYVFNT GTPAHMAWSI 
301:	LALGFFSSAI YTTIITLGSQ QTKVPSPKLV NFVLTCGTIG TMLTFVVTGP IVEHSGPQAA 
361:	LLTANGLYAV VFVMCFLLGF VSRHRQHNTL TSH