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2.A.1.8.5
Nitrate/nitrite transporter/antiporter, CrnA/NrtA (Unkles et al., 1991; Beckham et al. 2010). The nitrate signature sequences (NS1 and NS2) in TMSs 5 and 11 and arg residues in TMSs 2 and 8 may influence substrate binding (Unkles et al., 2012).

Accession Number:P22152
Protein Name:CrnA
Length:507
Molecular Weight:54925.00
Species:Emericella nidulans (Aspergillus nidulans) [162425]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate nitrate, Nitrite

Cross database links:

RefSeq: XP_658612.1   
Entrez Gene ID: 2876788   
Pfam: PF07690   
KEGG: ani:AN1008.2   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015103 F:inorganic anion transmembrane transporter a...
GO:0015698 P:inorganic anion transport
GO:0042128 P:nitrate assimilation
GO:0055085 P:transmembrane transport

References (2)

[1] “crnA encodes a nitrate transporter in Aspergillus nidulans.”  Unkles S.E.et.al.   1986367
[2] “Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.”  Galagan J.E.et.al.   16372000

External Searches:

  • Search: DB with
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  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDFAKLLVAS PEVNPNNRKA LTIPVLNPFN TYGRVFFFSW FGFMLAFLSW YAFPPLLTVT 
61:	IRDDLDMSQT QIANSNIIAL LATLLVRLIC GPLCDRFGPR LVFIGLLLVG SIPTAMAGLV 
121:	TSPQGLIALR FFIGILGGTF VPCQVWCTGF FDKSIVGTAN SLAAGLGNAG GGITYFVMPA 
181:	IFDSLIRDQG LPAHKAWRVA YIVPFILIVA AALGMLFTCD DTPTGKWSER HIWMKEDTQT 
241:	ASKGNIVDLS SGAQSSRPSG PPSIIAYAIP DVEKKGTETP LEPQSQAIGQ FDAFRANAVA 
301:	SPSRKEAFNV IFSLATMAVA VPYACSFGSE LAINSILGDY YDKNFPYMGQ TQTGKWAAMF 
361:	GFLNIVCRPA GGFLADFLYR KTNTPWAKKL LLSFLGVVMG AFMIAMGFSD PKSEATMFGL 
421:	TAGLAFFLES CNGAIFSLVP HVHPYANGIV SGMVGGFGNL GGIIFAIIFR YSHHDYARGI 
481:	WILGVISMAV FISVSWVRPV PKSQMRE