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2.A.1.82.6
Synaptic vesicle 2-related protein, SVOPL, of 492 aas and 12 TMSs in a 6 + 1 + 5 TMS arrangement.  Gene disruption gives rise to neurocognitive disabilities (Nilsson et al. 2017), and mutations can give rise to retinal dystrophies, hereditary blinding disorders (Patel et al. 2018).  SVOPL is also a potential cell survival gene that undergoes allelic switching (Boot et al. 2019).

Accession Number:Q8N434
Protein Name:Putative transporter SVOPL
Length:492
Molecular Weight:53991.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MATKPTEPVT ILSLRKLSLG TAEPQVKEPK TFTVEDAVET IGFGRFHIAL FLIMGSTGVV 
61:	EAMEIMLIAV VSPVIRCEWQ LENWQVALVT TMVFFGYMVF SILFGLLADR YGRWKILLIS 
121:	FLWGAYFSLL TSFAPSYIWF VFLRTMVGCG VSGHSQGLII KTEFLPTKYR GYMLPLSQVF 
181:	WLAGSLLIIG LASVIIPTIG WRWLIRVASI PGIILIVAFK FIPESARFNV STGNTRAALA 
241:	TLERVAKMNR SVMPEGKLVE PVLEKRGRFA DLLDAKYLRT TLQIWVIWLG ISFAYYGVIL 
301:	ASAELLERDL VCGSKSDSAV VVTGGDSGES QSPCYCHMFA PSDYRTMIIS TIGEIALNPL 
361:	NILGINFLGR RLSLSITMGC TALFFLLLNI CTSSAGLIGF LFMLRALVAA NFNTVYIYTA 
421:	EVYPTTMRAL GMGTSGSLCR IGAMVAPFIS QVLMSASILG ALCLFSSVCV VCAISAFTLP 
481:	IETKGRALQQ IK