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2.A.1.9.1
High affinity Pi uptake porter, SUL1, Sul-1, SFP2 of 859 aas and 10 TMSs. (also functions in Mn2+ homeostasis); may transport a phosphate·Mn2+ complex (Jensen et al., 2003). Also takes up selenite (Lazard et al., 2010).  May be a "transceptor", combining transport and receptor functions (Diallinas 2017).
 

Accession Number:P25297
Protein Name:Ph84 aka PHO84 aka YML123C aka YM7056.03C
Length:587
Molecular Weight:64382.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate phosphate, Manganese 2+, Selenite

Cross database links:

Genevestigator: P25297
eggNOG: fuNOG07250
HEGENOM: HBG744844
DIP: DIP-5072N
RefSeq: NP_013583.1   
Entrez Gene ID: 854916   
Pfam: PF00083   
KEGG: sce:YML123C   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0005315 F:inorganic phosphate transmembrane transport...
GO:0005384 F:manganese ion transmembrane transporter act...
GO:0005515 F:protein binding
GO:0006828 P:manganese ion transport
GO:0006817 P:phosphate transport
GO:0006797 P:polyphosphate metabolic process
GO:0055085 P:transmembrane transport

References (7)

[1] “The PHO84 gene of Saccharomyces cerevisiae encodes an inorganic phosphate transporter.”  Bun-Ya M.et.al.   2038328
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.”  Bowman S.et.al.   9169872
[3] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[4] “A proteomics approach to understanding protein ubiquitination.”  Peng J.et.al.   12872131
[5] “Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.”  Li X.et.al.   17330950
[6] “Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.”  Smolka M.B.et.al.   17563356
[7] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSSVNKDTIH VAERSLHKEH LTEGGNMAFH NHLNDFAHIE DPLERRRLAL ESIDDEGFGW 
61:	QQVKTISIAG VGFLTDSYDI FAINLGITMM SYVYWHGSMP GPSQTLLKVS TSVGTVIGQF 
121:	GFGTLADIVG RKRIYGMELI IMIVCTILQT TVAHSPAINF VAVLTFYRIV MGIGIGGDYP 
181:	LSSIITSEFA TTKWRGAIMG AVFANQAWGQ ISGGIIALIL VAAYKGELEY ANSGAECDAR 
241:	CQKACDQMWR ILIGLGTVLG LACLYFRLTI PESPRYQLDV NAKLELAAAA QEQDGEKKIH 
301:	DTSDEDMAIN GLERASTAVE SLDNHPPKAS FKDFCRHFGQ WKYGKILLGT AGSWFTLDVA 
361:	FYGLSLNSAV ILQTIGYAGS KNVYKKLYDT AVGNLILICA GSLPGYWVSV FTVDIIGRKP 
421:	IQLAGFIILT ALFCVIGFAY HKLGDHGLLA LYVICQFFQN FGPNTTTFIV PGECFPTRYR 
481:	STAHGISAAS GKVGAIIAQT ALGTLIDHNC ARDGKPTNCW LPHVMEIFAL FMLLGIFTTL 
541:	LIPETKRKTL EEINELYHDE IDPATLNFRN KNNDIESSSP SQLQHEA