TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.9.7
Organic phosphate (glycerophosphoinositol and glycerophosphocholine, the products of phospholipase-B mediated deacylation of phosphatidylinositol and phosphatidylcholine, respectively) transport protein GIT1 (Almaguer et al. 2006).

Accession Number:P25346
Protein Name:Probable metabolite transport protein GIT1
Length:518
Molecular Weight:57322.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Glycerophosphoinositol, glycerophosphocholine

Cross database links:

Genevestigator: P25346
eggNOG: COG0477
HEGENOM: HOG000214987
DIP: DIP-4626N
Entrez Gene ID: 850462   
Pfam: PF00083   
KEGG: sce:YCR098C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0001406 F:glycerophosphodiester transmembrane transporter activity

References (3)

[1] “Sequence of the HMR region on chromosome III of Saccharomyces cerevisiae.”  Sor F.et.al.   1574927
[2] “The complete DNA sequence of yeast chromosome III.”  Oliver S.G.et.al.   1574125
[3] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MEDKDITSVN EKEVNENTNP RIIKYDAERR ATRTETSKKD KWKNIVTIIA SGFALISDGY 
61:	VNGSMSMLNK VFVMEYGKKN YSSKVSTRVS NAALVGIIFG QFFMGIAADY YSRKSCILVA 
121:	TAILVIGSAL CAASHGTTVP GMFWMLTVMR GLVGIGVGAE YPTSTLSANE SANEYTTTKR 
181:	GGILVMVTNL PLAFGGPFAT IIFLIVYKIC SGTKHLEAIW RTVFAIGCFW PLSVFYFRWK 
241:	TATTEVYEKG RIKRNIPYFL ALKFYWKRLL GTCGTWFMYD FVTFPNGIFS STIISSVIKD 
301:	QNDLVKVAEW NLLLGVLAVL GVPIGAYLSD RIGRKYTLMF GFSGYIIFGL IIGCAYDQLK 
361:	KITPLFIIFY AFMNMLGNAG PGDMLGVISS EASATAVRGV FYGLSAVTGK IGSVVGVECF 
421:	QPIRDNLGAR WTFIIAAICG LIGIIITYFF VPHSLESDLM KQDVEFHNYL VSNGWTGKMG 
481:	FDETDEESMV RTIEVEENGT NCSKKNAEII SVRQVDQS