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2.A.102.3.1
Orf of 269 aas and 6 TMSs

Accession Number:P0AD30
Protein Name:YfcA aka b2327 aka JW2324
Length:269
Molecular Weight:28643.00
Species:Escherichia coli [83333]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P0AD30 P0AD30
EchoBASE: EB1134 EB1134
EcoGene: EG11144 EG11144
eggNOG: COG0730 COG0730
HEGENOM: HBG580184 HBG580184
RefSeq: AP_002927.1    NP_416830.1   
Entrez Gene ID: 946808   
Pfam: PF01925   
BioCyc: EcoCyc:EG11144-MONOMER    ECOL168927:B2327-MONOMER   
KEGG: ecj:JW2324    eco:b2327    ecj:JW2324    eco:b2327   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (10)

[1] “Cloning and characterization of mepA, the structural gene of the penicillin-insensitive murein endopeptidase from Escherichia coli.”  Keck W.et.al.   2187143
[2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[6] “Cloning and characterization of mepA, the structural gene of the penicillin-insensitive murein endopeptidase from Escherichia coli.”  Keck W.et.al.   2187143
[7] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[8] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[9] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[10] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	METFNSLFMV SPLLLGVLFF VAMLAGFIDS IAGGGGLLTI PALMAAGMSP ANALATNKLQ 
61:	ACGGSISATI YFIRRKVVSL SDQKLNIAMT FVGSMSGALL VQYVQADVLR QILPILVICI 
121:	GLYFLLMPKL GEEDRQRRMY GLPFALIAGG CVGFYDGFFG PAAGSFYALA FVTLCGFNLA 
181:	KATAHAKLLN ATSNIGGLLL FILGGKVIWA TGFVMLVGQF LGARMGSRLV LSKGQKLIRP 
241:	MIVIVSAVMS AKLLYDSHGQ EILHWLGMN