TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*2.A.103.1.1









Cell division protein, FtsW.  May flip lipid II (involved in cell wall synthesis) across the cytoplasmic membrane.  R145 and K153 in TMS 4 (of 10) are esesential for this transport activity (Mohammadi et al. 2014).  There is some controversy about this transport function (Young 2014; Sham et al. 2014).  See TC#2.A.66.4.3 for the alternative explanation.

Bacteria
Proteobacteria
FtsW of E. coli (P0ABG4)
*2.A.103.1.2









Rod shape determining protein, RodA.  A proposed flippase for a lipid-linked disaccharide-pentapeptide cell wall precursor, but this proposal is controversial (Sham et al. 2014; Young 2014).

Bacteria
Proteobacteria
RodA of E. coli (P0ABG7)
*2.A.103.1.3









Sporulation protein, SpoVE.

Bacteria
Firmicutes
SpoVE of Bacillus subtilis (P07373)
*2.A.103.1.4









FtsW of 524 aas

Bacteria
Actinobacteria
FtsW of Mycobacterium tuberculosis
*2.A.103.1.5









FtsW of 361 aas

Bacteria
Aquificae
FtsW of Hydrogenobacter thermophilus
*2.A.103.1.6









FtsW of 385 aas

Bacteria
Thermotogae
FtsW of Marinitoga piezophila
*2.A.103.1.7









FtsW of 448 aas and 123 TMSs

Bacteria
Actinobacteria
FtsW of Tropheryma whipplei (strain Twist) (Whipple's bacillus)
*2.A.103.1.8









Bacteria
Chlamydiae/Verrucomicrobia group
MrdB of Chlamydophila psittaci (Chlamydia psittaci)
*2.A.103.1.9









Lipid flippase involved in cell envelope biogenesis, FtsW, of 456 aas and 10 TMSs (Bush et al. 2015).

Bacteria
Actinobacteria
FtsW of Streptomyces coelicolor
*2.A.103.1.10









Rod shape-determining protein Rod, of 424 aas and 10 TMSs.

Bacteria
Bacteroidetes
RodA of Lacinutrix venerupis