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2.A.106.2.3
Golgi Ca2+:H+ and/or Mn2+:H+ antiporter, Gdt1 (GCR-1-dependent translation factor 1) or TMEM165 (Demaegd et al., 2013).  Involved in ion homeostasis (Dulary et al. 2016).

Accession Number:P38301
Protein Name:GCR1-dependent translation factor 1
Length:280
Molecular Weight:30341.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Calcium 2+, protons, Manganese 2+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGNMIKKASL IALLPLFTAA AAAATDAETS MESGSSSHLK SFLMSVSMIG LSEIGDKTFL 
61:	IAALMAMRHK RVLVFSAAAT SLAIMTILSG VVGHSAVAFL SERYTAFFAG ILFLVFGYKL 
121:	TMEGLEMSKD AGVEEEMAEV EEEIAIKDMN QDMDDVEKGG DTAYDKQLKN ASIGKKIVHR 
181:	IRELASFMFS PVWVQIFLMV FLGELGDRSQ ISIIAMATDS DYWYVIAGAV IGHAICSGLA 
241:	VVGGKLLATR ISIRTITLAS SLLFFIFALM YIYQAFTTQD