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2.A.107.1.1
The manganese ion efflux pump, MntP (YebN).  Regulated by the MntR regulatory protein and the MntS sRNA (Waters et al., 2011). This family has been designated the DUF204 family.

Accession Number:P76264
Protein Name:YEBN_ECOLI
Length:188
Molecular Weight:20117.00
Species:Escherichia coli [83333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Mn2+

Cross database links:

Genevestigator: P76264
EchoBASE: EB3768
EcoGene: EG14012
eggNOG: COG1971
HEGENOM: HBG709685
RefSeq: AP_002440.1    NP_416335.4   
Entrez Gene ID: 946341   
Pfam: PF02659   
BioCyc: EcoCyc:G6999-MONOMER    ECOL168927:B1821-MONOMER   
KEGG: ecj:JW5830    eco:b1821   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (5)

[1] “A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map.”  Itoh T.et.al.   9097040
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Fur regulon in Gram-negative bacteria. Identification and characterization of new iron-regulated Escherichia coli genes by a fur titration assay.”  Stojiljkovic I.et.al.   8107138
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MNITATVLLA FGMSMDAFAA SIGKGATLHK PKFSEALRTG LIFGAVETLT PLIGWGMGML 
61:	ASRFVLEWNH WIAFVLLIFL GGRMIIEGFR GADDEDEEPR RRHGFWLLVT TAIATSLDAM 
121:	AVGVGLAFLQ VNIIATALAI GCATLIMSTL GMMVGRFIGS IIGKKAEILG GLVLIGIGVQ 
181:	ILWTHFHG