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2.A.108.2.5
Ferrous iron uptake permease, EfeU

Accession Number:P39595
Protein Name:Ferrous iron permease EfeU
Length:481
Molecular Weight:52388.00
Species:Bacillus subtilis (strain 168) [224308]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate iron

Cross database links:

eggNOG: COG0672
HEGENOM: HOG000100914
Entrez Gene ID: 938520   
Pfam: PF03239   
KEGG: bsu:BSU38280   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006811 P:ion transport
GO:0055072 P:iron ion homeostasis
GO:0055085 P:transmembrane transport

References (4)

[1] “Bacillus subtilis genome project: cloning and sequencing of the 97 kb region from 325 degrees to 333 degrees.”  Glaser P.et.al.   7934828
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.”  Barbe V.et.al.   19383706
[4] “Role of the Fur regulon in iron transport in Bacillus subtilis.”  Ollinger J.et.al.   16672620

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MARGLALILF SLLMVFGSAA HAEDDPIAAL IQLNKQMIKS VKDGDMDSAQ QTFDTFKAKW 
61:	KKEEPSIKKE NLSSHSEMDA NIAMISLSFI NQDARKLKTQ LEELASHLET YQQAVVLKKT 
121:	SSGQSRASLT AYIQSLKDTK QFIEKKQLDE ASSAIDNLVT SWLAVEGDVV SQSKEAYTTS 
181:	EENLALMKAE IGSHPEKVSK QIDEMIQLLE PIASSSYSWW DAALIPVREG MEALLVIGAL 
241:	LTMTKKARVT RSSTWIWGGA SAGMAVSLAA GIGVTVLFSS SVFGENNFLL GGVTGVLSAV 
301:	MLLYVGVWLH RNASMDKWRE KINIQKSQAL KKRSLLSFAL IAFLAVVREG LETVIFFIGL 
361:	VGKLPLTELI GGTAAGLIVL VIVGVLMIKL GMRIPLKPFF LLSMAVVLYM CVKFLGTGVH 
421:	SLQLAGILPS DAESWLPSVS VLGIYPSVYS TIPQMLILLF LLIALVSEAA KHFTNGKELT 
481:	K