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2.A.11.1.3
Citrateā€¢Me2+ (Fe2+/Mn2+ preferring):H+ symporter, CitM

Accession Number:Q8DUC7
Protein Name:Putative Mg2+/citrate transporter
Length:467
Molecular Weight:50921.00
Species:Streptococcus mutans [1309]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Fe2+, Mn2+, H+

Cross database links:

HEGENOM: HBG297065
RefSeq: NP_721408.1   
Entrez Gene ID: 1028346   
Pfam: PF03600   
BioCyc: SMUT210007:SMU_1013C-MONOMER   
KEGG: smu:SMU.1013c   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015137 F:citrate transmembrane transporter activity
GO:0015746 P:citrate transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen.”  Ajdic D.J.et.al.   12397186

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLLTILAYAM IIVFMYVVMK KKMSPFTALI IVPLVAVIIV ILTNSANFTA DKSFVEFLGG 
61:	DKISHNLTAI GPMVLYGINN TAQTGIMLLF AILYFSLMLD AGLFDPITEK MIRFAKGDPM 
121:	KVLIATAIVS AAVSLNGDGT TTTLICCSAF LPIYKKLNMK IMNLGVLIIL QNTIMNLLPW 
181:	GGPTARAMSV LNVGSEILGY LAPGMILSLL YVIFFVARSM GKKERKRLGV TELSDKEITE 
241:	LITVNDPDTL KIRRPQNFWF NGILTLILIA WLVAGSFISA IEMPSLLLFA LGTCIALMVN 
301:	YPNLKEQSKR ISENAGDAVQ VVILVFAAGI FMGLFQGSGM AGALAQSFTT IIPKQLAGFW 
361:	GLVIAFISAP GTFFLSNDGF YYGIMPVLAE AGAKYGFDNV AMALASLMGQ AFHLLSPLVA 
421:	FIYLLLRLTG LDMGEWQRES AKYALVVFII FVVTILIVGR LPFYIPQ