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2.A.110.1.3
HRG-4 heme transporter (Rajagopal et al. 2008).

Accession Number:Q20106
Protein Name:Heme transporter hrg-4
Length:207
Molecular Weight:23574.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Heme

Cross database links:

eggNOG: NOG284582
HEGENOM: HOG000017991
Entrez Gene ID: 185380   
KEGG: cel:F36H1.5   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0020037 F:heme binding
GO:0015232 F:heme transporter activity

References (2)

[1] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916
[2] “Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins.”  Rajagopal A.et.al.   18418376

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTHAFLVIKY YWHIFFVEFS KCTSSTRGSA KKEHVNYRMT AENRGFCQLI CHINVRIGWT 
61:	IFGIVFGISA ILTYAIKFHN WSATATTAIA TLFACETLYL YWALKKNTIV NWKSSTFQLM 
121:	IWPNVFIGLL GLLGCLVCYI IAGITHQGAG SIQAMYGENL WFTGSWSLVI TKWTWQNAFF 
181:	ARKYLNKIGT ASEDGDIDDD DVEVIKS