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2.A.111.1.1
Probable Na+/H+ antiporter, NhaE of 489 aa.

Accession Number:Q8F285
Protein Name:Putative Transporter
Length:489
Molecular Weight:54379.00
Species:Leptospira interrogans [173]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate sodium, protons

Cross database links:

HEGENOM: HBG307799
RefSeq: NP_713072.1   
Entrez Gene ID: 1152234   
BioCyc: LINT189518:LA2891-MONOMER   
KEGG: lil:LA2891   

References (1)

[1] “Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing.”  Ren S.-X.et.al.   12712204

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIQTMKQKIT SVFLAILLTL PASMLLADEP VGNPQSTVQD SSHTQEANSG HHEVEGEDLP 
61:	YWTVIPFALI LLSIALLPIV SHTTSHWWES NTNKLILSLI LGAISFVILV LHGWFGKIVH 
121:	TLVFEYVPFI ILLGSLFYIS GGIRLKGDIE ATPLNNTIFL IIGTFLASFI GTTGASMLLI 
181:	RPILKTNSER KHVVHTVVFF IFLVSNIGGS LTPLGDPPLF LGYLIGVPFT WTFKLLPELI 
241:	VAGILLLILY FIWDSIAYKK ETAKDLKKDH THKEKISLEG QVNFIWLLGV VLSVAYLNQN 
301:	YIPAIHENPY IAFIREAVLI GLIFVSKFTT KGHVREHNKF TLHPIQEVAY LFIGIFITMI 
361:	PALILLEHHG KELGITETWQ FFWVTGLFSG VLDNAPTYLT FLSLAKGTLG LNNVAQILAD 
421:	PHAESILKAI SVGAVFMGAL TYIGNAPNFM VKSVAEENKI KMPSFGGYVL YSFGILVPTF 
481:	LLLTFIFFR