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2.A.112.1.12
Xkr9 of 650 aas.  Catalyzes phosphatidyl serine flipping from the inner leaflet to the outer leaflet of the cell membrane to signal appoptosis.  It has a C-terminal caspase recognition signal that may play an important role.  Xkr4, 8 and 9 have this activity and have several essential residues in TMS2 and cytoplasmic loop 2 (Suzuki et al. 2014).

Accession Number:Q5GH70
Protein Name:XK-related protein 9
Length:373
Molecular Weight:43406.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate phospholipids

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKYTKQNFMM SVLGIIIYVT DLIVDIWVSV RFFHEGQYVF SALALSFMLF GTLVAQCFSY 
61:	SWFKADLKKA GQESQHCFLL LHCLQGGVFT RYWFALKRGY HAAFKYDSNT SNFVEEQIDL 
121:	HKEVIDRVTD LSMLRLFETY LEGCPQLILQ LYILLEHGQA NFSQYAAIMV SCCAISWSTV 
181:	DYQVALRKSL PDKKLLNGLC PKITYLFYKL FTLLSWMLSV VLLLFLNVKI ALFLLLFLWL 
241:	LGIIWAFKNN TQFCTCISME FLYRIVVGFI LIFTFFNIKG QNTKCPMSCY YIVRVLGTLG 
301:	ILTVFWVCPL TIFNPDYFIP ISITIVLTLL LGILFLIVYY GSFHPNRSAE TKCDEIDGKP 
361:	VLRECRMRYF LME