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2.A.12.1.10
The microsporidial ATP/ADP exchanger, NTT1 (Km= 11μM; cell surface localized when in the host cell; Tsaousis et al. 2008).

Accession Number:Q8SRA2
Protein Name:ADP/ATP CARRIER PROTEIN 1 (NTT1)
Length:559
Molecular Weight:63516.00
Species:Encephalitozoon cuniculi [6035]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate ATP, ADP

Cross database links:

eggNOG: euNOG18588
RefSeq: NP_597260.1   
Entrez Gene ID: 859682   
KEGG: ecu:ECU08_1300   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0006810 P:transport

References (2)

[1] “A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi.”  Tsaousis A.D.et.al.   18449191
[2] “Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi.”  Katinka M.D.et.al.   11719806

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNEVENNNHS FPREDIPTED EIEEEANSRQ GILRYFRVAR AEYTKFALLG LMFGIIGFIY 
61:	SFMRILKDMF VMVRQEPTTI LFIKIFYILP VSMALVFLIQ YMLGTKTVSR IFSIFCGGFA 
121:	SLFFLCGAVF LIEEQVSPSK FLFRDMFIDG KMSSRSLNVF KSMFLTLNEP LATIVFISAE 
181:	MWGSLVLSYL FLSFLNESCT IRQFSRFIPP LIIITNVSLF LSATVAGAFF KLREKLAFQQ 
241:	NQVLLSGIFI FQGFLVVLVI FLKIYLERVT MKRPLFIVSS GSRRKKAKAN VSFSEGLEIM 
301:	SQSKLLLAMS LIVLFFNISY NMVESTFKVG VKVAAEYFNE EKGKYSGKFN RIDQYMTSVV 
361:	VICLNLSPFS SYVETRGFLL VGLITPIVTL MAIVLFLGSA LYNTSMEESG LGIVNGLFPG 
421:	GKPLYVLENY FGVIFMSLLK ITKYSAFDIC KEKLGMRINP TYRARFKSVY DGIFGKLGKS 
481:	IGSIYGLLMF EALDTEDLRK ATPITAGIIF IFIVMWVKAI IYLSRSYESA VQHNRDVDID 
541:	MTEKAKKSLE TPEEPKVVD