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2.A.12.1.11
The microsporidial ATP/ADP exchanger, NTT2 (Km= 20μM; present in spores; localized to the cell surface; Tsaousis et al., 2008).

Accession Number:Q8SUF9
Protein Name:Similarity to ADP/ATP CARRIER PROTEIN (NTT2)
Length:553
Molecular Weight:62160.00
Species:Encephalitozoon cuniculi [6035]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate ATP, ADP

Cross database links:

eggNOG: euNOG18588
RefSeq: NP_586169.1   
Entrez Gene ID: 859818   
KEGG: ecu:ECU10_0540   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0006810 P:transport

References (2)

[1] “A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi.”  Tsaousis A.D.et.al.   18449191
[2] “Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi.”  Katinka M.D.et.al.   11719806

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSEIGSSVPV NENRPLLTED EVEAQANSST VWPLSRIRVA RCEWKLWGSL AFIFGASAYI 
61:	YSFSRVMKDS FVLSRQLPIA ISFLKTCFVL PISVIVTGIV QKLLVTRTIS KVFDYTLIAF 
121:	SFLYLLIGMV LLPFAEKIQP GLYFSRDIFA DDKMAYKGFE FLFAIFLIFN EWTTSFVYVC 
181:	AELFGSLVVQ FMFLAFANEA LTIRQSTRMM PLFYVISNIL LLLSSESTSF YSKKVREWDY 
241:	KKTCLITNSF FAVFGAMIAV TYLVKKYAEN TILKKQLFIR TEGVAKKKGR KSSAGFSESM 
301:	KLMAQSKFLV AMVMNALFYY AGTNLIESSW KNGISVAADA NNMEKRAYSA SIVSGEQRVV 
361:	GALVAIILLT PISTLVQTHG WITMAIVPPL VTLVSSLVIF GSAFFNYSNY PEGKTSVILS 
421:	SLVKGYKPNF YLECNIGIYC VSGMKIAKYA FYDISKEAIS LQIDPLYRPR LKAVYDGLCG 
481:	KLGKSIGSLY AMFWSVMGYN DVRAAAPITL GMWLIISPIW IYSVIYLNRK YNQSIQTSSP 
541:	IDLDLFSGKK DLE