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2.A.12.1.13
The microsporidial ATP/ADP exchanger, NTT4 (Km= 2μM; present on the cell surface when in the host cell; Tsaousis et al., 2008).

Accession Number:Q8SUG7
Protein Name:Similarity to ADP/ATP CARRIER PROTEIN (NTT4)
Length:536
Molecular Weight:60856.00
Species:Encephalitozoon cuniculi [6035]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate ATP, ADP

Cross database links:

eggNOG: euNOG18588
RefSeq: NP_586157.1   
Entrez Gene ID: 859806   
KEGG: ecu:ECU10_0420   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0006810 P:transport

References (2)

[1] “A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi.”  Tsaousis A.D.et.al.   18449191
[2] “Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi.”  Katinka M.D.et.al.   11719806

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSENREIDAT DRRDKTFDKE KLRPHVYSSV AGGMRSTSGD TKAVLLFSLL FALLSYIDAF 
61:	LYVLGDMVMM NTQMPSSILF IKSVLVLPMT FFFIVIVQKG LRYLSQPRML EVILIISSVF 
121:	FLLFGFVIWP YCKRLQPDFF WSRDIFSDGK MKTRHLDFFF PIFLVFSEWA STMLYLVAEL 
181:	WGSLIISFMF FSRAIHQCTE AQVKKFLPTI SLISAVVFLS SGLLTKSLNS RRDALPYHEK 
241:	ERLFSQVFIV TSALTVMSAI TSFFTDRALA KDDPRHKGKK EHKVRKIGFA GSLKMMQKSR 
301:	FLRAMTESVV AASVCSNIFE AIYRGGIVLG AVQSSTSKSS YMNRLNAMAQ IITSIFLLVM 
361:	FFKPATHLIE RRGWFPVAIT APIVAIITLV LFFPMVFFNN ITEGDLIASG EEYVGSFVLE 
421:	NYTGMFLTTI IRISKYCFFD VAKEAASIRV SPVHRHSFRG IHDGLGINIG KTIGSVYCTL 
481:	VTVVFDVRDV RNVVSVSTVF VGVFCVIWIR SILHINKKYK ESIERNDFIN VELAEG