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2.A.12.1.14
The nucleotide (ATP/ADP) exchanger NTT1 (Schmitz-Esser et al., 2008) (KMs for ATP and ADP ~ 250 μM)

Accession Number:B0RZB7
Protein Name:ATP/ADP translocase
Length:521
Molecular Weight:57946.00
Species:Lawsonia intracellularis [29546]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate ATP, ADP

Cross database links:

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0005471 F:ATP:ADP antiporter activity
GO:0006810 P:transport

References (1)

[1] “Lawsonia intracellularis contains a gene encoding a functional rickettsia-like ATP/ADP translocase for host exploitation.”  Schmitz-Esser S.et.al.   18606736

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	TGGSMPEEDF TGWRAILWPV YNFELKKFLP MGLMMLCILF IYRLVRDIKD TLMVSQATGG 
61:	GAETLGFLKL WGVTPSAILF MIIFVKLANK LSKANLFYTI VSFFLGFFVL FGLVIYPLTE 
121:	YFHMSYETIS HLQTTMPRLY WVWPIIGNWS YAIFYILSEL WGSVVLSALF WQFANEITKI 
181:	SEAKRFYSLF GFVGNFGLLA SGSIIIICAN IAKNSAVDGT IDVFGESLKY QMLAVLFFGL 
241:	LLLYLYRWMN KNVLTDPKLY TPGAGSKKKS KPKLGLIEST KCILTSRYLL MISALVIGYG 
301:	ISINLVEGVW KGQIKLLYPD PNDFNVLMGK LALTTGFVTI IIMLIGANIL RRFSWRTAAL 
361:	ITPIFLMATS VIFFGVIIYE NKMGLDATLW GFGVLLLAVV VGLMQNAFSK GVKYSLFDAT 
421:	KQMAYIPLDP ELKVKGQAAV EILAGRLGKS GGAAIQSIML LIIGGNVTLA SQVEFLGSAV 
481:	LVVVAFWIIS VFGLSKQFET LQSEQQAEEA NSKENKEVKD G