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2.A.12.1.17
Nucleoside triphosphate:H+ symporter.  Transports ATP, GTP, CTP and UTP (Tjaden et al. 1999).

Accession Number:Q9X9D2
Protein Name:Npt2
Length:540
Molecular Weight:59648.00
Species:Chlamydia trachomatis [813]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2 / Cytoplasmic side3
Substrate ATP, GTP, CTP, UTP, H+

Cross database links:

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0005471 F:ATP:ADP antiporter activity
GO:0006810 P:transport

References (1)

[1] “Two nucleotide transport proteins in Chlamydia trachomatis, one for net nucleoside triphosphate uptake and the other for transport of energy.”  Tjaden J.et.al.   9973346

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSSEVKSFSK FRGYFFPIYR SEFSKFIPLF FLAFFVGVNY ALLKTTKDSL VLVGSRAGAE 
61:	VIPFLKVWGI VPGAVIVTMI YGWMSRRYSR GTVFISLVGG FLGFFALFAT VIYPIGDALH 
121:	LNKLAAKLQS ILPPGGRGFV VMVQYWSYSL YYVMSELWSS VVLSTLFWGV ANHITSVREA 
181:	GRFYALINTG LNLSSVFAGE VSLWLGRSPV IAFPMAVDPW HEMLLNITLL IVLAGGVILY 
241:	LYQKLDRLMD ETSMLEEGLA AEMSVAQLKK EKKRSKAKAK SLFALLLRSR YLLGIAVVVL 
301:	SYNLVIHLFE VVWKDQVCRI YASRVEFNSY MSRITTLTGI VSALAGIFAA GQTIRRWGWT 
361:	VGALVPPLTI LITGALFFGA IYAVKGDAMI FGGILGISPL VLTAWLGGVQ NVFSRAIKFT 
421:	YFDQTKEMAF IPLEDDEKNY GKAAIDGVIS RVGKSGGSLV YQGLLIIFSS VAASLNAITI 
481:	VLLLALGSWI FVIAWLGREY TAKTETLVRV NASEEDVLQE EREASSLVDA ESREEPVTTL