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2.A.123.1.8
Rga (Recombination-activating gene 1) (Hamada et al., 2005)

Accession Number:Q9CXK4
Protein Name:Sugar transporter SWEET1
Length:221
Molecular Weight:24649.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate Sugars

Cross database links:

Genevestigator: Q9CXK4 Q9CXK4
eggNOG: roNOG12956 roNOG12956
HEGENOM: HBG716048 HBG716048
Entrez Gene ID: 19729   
Pfam: PF03083   
KEGG: mmu:19729    mmu:19729   

Gene Ontology

GO:0012505 C:endomembrane system
GO:0016021 C:integral to membrane
GO:0005634 C:nucleus
GO:0051119 F:sugar transmembrane transporter activity
GO:0006310 P:DNA recombination
GO:0045815 P:positive regulation of gene expression, epigenetic
GO:0000139 C:Golgi membrane
GO:0005886 C:plasma membrane

References (8)

[1] “Molecular cloning and characterization of a novel stromal cell-derived cDNA encoding a protein that facilitates gene activation of recombination activating gene (RAG)-1 in human lymphoid progenitors.”  Tagoh H.et.al.   8630032
[2] “The transcriptional landscape of the mammalian genome.”  Carninci P.et.al.   16141072
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Sugar transporters for intercellular exchange and nutrition of pathogens.”  Chen L.-Q.et.al.   21107422
[5] “Molecular cloning and characterization of a novel stromal cell-derived cDNA encoding a protein that facilitates gene activation of recombination activating gene (RAG)-1 in human lymphoid progenitors.”  Tagoh H.et.al.   8630032
[6] “The transcriptional landscape of the mammalian genome.”  Carninci P.et.al.   16141072
[7] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[8] “Sugar transporters for intercellular exchange and nutrition of pathogens.”  Chen L.-Q.et.al.   21107422

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEAGGVADSF LSSACVLFTL GMFSTGLSDL RHMQRTRSVD NIQFLPFLTT DVNNLSWLSY 
61:	GVLKGDGTLI IVNSVGAVLQ TLYILAYLHY SPQKHGVLLQ TATLLAVLLL GYGYFWLLVP 
121:	DLEARLQQLG LFCSVFTISM YLSPLADLAK IVQTKSTQRL SFSLTIATLF CSASWSIYGF 
181:	RLRDPYITVP NLPGILTSLI RLGLFCKYPP EQDRKYRLLQ T