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2.A.123.1.9
Sweet1: bidirectional low affinity glucose uniporter, Km = ~9mM (Does not transport mannose, fructose or galactose) (Chen et al. 2010). The structure is know, and three regions, each containing several well conserved essential residues, comprise the substrate-binding pocket, the extrafacial gate, and the intrafacial gate (Xuan et al. 2013; Tao et al. 2015)  

Accession Number:Q8L9J7
Protein Name:Bidirectional sugar transporter SWEET1
Length:247
Molecular Weight:27268.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate glucose

Cross database links:

Genevestigator: Q8L9J7
eggNOG: KOG1623
HEGENOM: HBG745285
Entrez Gene ID: 838744   
Pfam: PF03083   
KEGG: ath:AT1G21460   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0051119 F:sugar transmembrane transporter activity

References (3)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “Sugar transporters for intercellular exchange and nutrition of pathogens.”  Chen L.-Q.et.al.   21107422

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNIAHTIFGV FGNATALFLF LAPSITFKRI IKNKSTEQFS GIPYPMTLLN CLLSAWYGLP 
61:	FVSKDNTLVS TINGTGAVIE TVYVLIFLFY APKKEKIKIF GIFSCVLAVF ATVALVSLFA 
121:	LQGNGRKLFC GLAATVFSII MYASPLSIMR LVVKTKSVEF MPFFLSLFVF LCGTSWFVYG 
181:	LIGRDPFVAI PNGFGCALGT LQLILYFIYC GNKGEKSADA QKDEKSVEMK DDEKKQNVVN 
241:	GKQDLQV