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2.A.125.1.3
Solute carrier family 52, riboflavin transporter, member 2 (Porcine endogenous retrovirus A receptor 1) (PERV-A receptor 1) (Protein GPR172A) (Riboflavin transporter 3) (hRFT3) (Yonezawa and Inui 2013).

Accession Number:Q9HAB3
Protein Name:Solute carrier family 52, riboflavin transporter, member 2
Length:445
Molecular Weight:45777.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate riboflavin

Cross database links:

Genevestigator: Q9HAB3
eggNOG: NOG326568
HEGENOM: HOG000247012
Entrez Gene ID: 79581   
Pfam: PF06237   
KEGG: hsa:79581   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0004872 F:receptor activity
GO:0032217 F:riboflavin transporter activity

References (6)

[1] “Identification of receptors for pig endogenous retrovirus.”  Ericsson T.A.et.al.   12740431
[2] “Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain.”  Yao Y.et.al.   20463145
[3] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[4] “DNA sequence and analysis of human chromosome 8.”  Nusbaum C.et.al.   16421571
[5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[6] “Single-round selection yields a unique retroviral envelope utilizing GPR172A as its host receptor.”  Mazari P.M.et.al.   19307586

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAAPTPARPV LTHLLVALFG MGSWAAVNGI WVELPVVVKE LPEGWSLPSY VSVLVALGNL 
61:	GLLVVTLWRR LAPGKDEQVP IRVVQVLGMV GTALLASLWH HVAPVAGQLH SVAFLALAFV 
121:	LALACCASNV TFLPFLSHLP PRFLRSFFLG QGLSALLPCV LALVQGVGRL ECPPAPINGT 
181:	PGPPLDFLER FPASTFFWAL TALLVASAAA FQGLLLLLPP PPSVPTGELG SGLQVGAPGA 
241:	EEEVEESSPL QEPPSQAAGT TPGPDPKAYQ LLSARSACLL GLLAATNALT NGVLPAVQSF 
301:	SCLPYGRLAY HLAVVLGSAA NPLACFLAMG VLCRSLAGLG GLSLLGVFCG GYLMALAVLS 
361:	PCPPLVGTSA GVVLVVLSWV LCLGVFSYVK VAASSLLHGG GRPALLAAGV AIQVGSLLGA 
421:	VAMFPPTSIY HVFHSRKDCA DPCDS