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2.A.13.1.3
C4-dicarboxylate transporter, YhiT (probably transports succinate, fumarate, aspartate, asparagine, carbamoyl phosphate and dihydroorotate; Zaharik et al., 2007)

Accession Number:Q8ZLD2
Protein Name:YhiT
Length:439
Molecular Weight:46509.00
Species:Salmonella typhimurium [90371]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate C4-dicarboxylates, Succinate, Fumarate, aspartate, Asparagine, Carbamoyl phosphate, Dihydroorotate

Cross database links:

HEGENOM: HBG297083
RefSeq: NP_462500.1   
Entrez Gene ID: 1255122   
Pfam: PF03605   
BioCyc: STYP99287:STM3599-MONOMER   
KEGG: stm:STM3599   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015556 F:C4-dicarboxylate transmembrane transporter ...
GO:0015740 P:C4-dicarboxylate transport

References (1)

[1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFWTELCFIL VALMIGARIG GVFLGMVGGL GVGVMVFIFG LTPSTPPIDV ILIILSVVLA 
61:	AASLQASGGL DLLVKLAEKI LRRHPRYITL LAPFICYIFT FMSGTGHVVY SLLPVISEVA 
121:	RDSGIRPERP LSISVIASQQ AITASPISAA MAAMIGLMAP LGVSISTIMM ICVPATLIGV 
181:	AMGAIATFNK GKELKDDPEY QRRLAEGLIK PAQKESKNTV VTSRAKLSVA LFLTSAIVIV 
241:	LLGLIPALRP MVETAKGLQP LSMSAAIQIT MLSFACLIVL LCRPQVDQII SGTVFRAGAL 
301:	AIVCAFGLAW MSETFVNGHI ALIKAEVQTL LQQHTWLIAI MMFFVSAMVS SQAATTLILL 
361:	PLGLALGLPA YALIGSWPAV NGYFFIPVAG QCLAALAFDD TGTTRIGKYV LNHSFMRPGL 
421:	VNVIVSVIVG LLIGKMVLA