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2.A.15.1.2
Ectosine/glycine betaine/proline:Na+ symporter

Accession Number:Q79VE0
Protein Name:Choline-glycine betaine transporter and EctP protein
Length:615
Molecular Weight:67403.00
Species: [1718]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Ectosine, Glycine betaine, Proline, Na+

Cross database links:

HEGENOM: HBG682943
RefSeq: NP_601511.1    YP_226555.1   
Entrez Gene ID: 1020263    3343846   
Pfam: PF02028   
BioCyc: CGLU196627:CG2539-MONOMER   
KEGG: cgb:cg2539    cgl:NCgl2230   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (2)

[1] “Corynebacterium glutamicum is equipped with four secondary carriers for compatible solutes: identification, sequencing, and characterization of the proline/ectoine uptake system, ProP, and the ectoine/proline/glycine betaine carrier, EctP.”  Peter H.et.al.   9811661
[2] “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.”  Kalinowski J.et.al.   12948626

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSSNIAITTE PEGKNKKGLK SDPFIFSISV GFIVVFVIAT IALGEKARTT FSAIAGWLLE 
61:	NLGWMYIGGV SLVFIFLMGI FASRYGRVKL GDDDDDPEHT LIVWFCMLFA GGVGAVLMFW 
121:	GVAEPINHAF NVPMANEESM SEAAIVQAFA YTFYHFGIHM WVIMALPGLS LGYFIYKRKL 
181:	PPRLSSVFSP ILGKHIYSTP GKLIDVLAIV GTTFGIAVSV GLGVLQINAG MNKLWSTPQV 
241:	SWVQLLIILI ITAVACISVA SGLDKGIKLL SNINIAMAVA LMFFILFTGP TLTLLRFLVE 
301:	SFGIYASWMP NLMFWTDSFQ DNPGWQGKWT VFYWAWTICW SPYVGMFVAR ISRGRTVREF 
361:	IGGVLALPAI FGVVWFSIFG RAGIEVELSN PGFLTQPTVV EGDVPAALFN VLQEYPLTGI 
421:	VSAFALVIIV IFFITSIDSA ALVNDMFATG AENQTPTSYR VMWACTIGAV AGSLLIISPS 
481:	SGIATLQEVV IIVAFPFFLV QFVMMFSLLK GMSEDAAAVR RVQTRQWEKT DTPEKLEEHS 
541:	SQPAPGYDDE GNPLPMPALE HDEDGNIVIP GNVVIEGDLG VVGDVVDDPE EAQEMGSRFK 
601:	IVEQTRPQSR DEYDI