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2.A.15.2.2
The L-carnitine:γ-butyrobetaine antiporter, CaiT.  The x-ray structure is known at 2.3 Å resolution (Schulze et al., 2010).  

Accession Number:B4EY22
Protein Name:L-carnitine/gamma-butyrobetaine antiporter
Length:514
Molecular Weight:57471.00
Species:Proteus mirabilis (strain HI4320) [529507]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Gamma-butyrobetaine, Carnitine

Cross database links:

HEGENOM: HBG682943
Entrez Gene ID: 6803117   
Pfam: PF02028   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015297 F:antiporter activity

References (2)

[1] “Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility.”  Pearson M.M.et.al.   18375554
[2] “Structural basis of Na(+)-independent and cooperative substrate/product antiport in CaiT.”  Schulze S.et.al.   20829798
Structure:
2WSW   4M8J     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MSKDNKKAGI EPKVFFPPLI IVGILCWLTV RDLDASNEVI NAVFSYVTNV WGWAFEWYMV 
61:	IMFGGWFWLV FGRYAKKRLG DEKPEFSTAS WIFMMFASCT SAAVLFWGSI EIYYYISSPP 
121:	FGMEGYSAPA KEIGLAYSLF HWGPLPWATY SFLSVAFAYF FFVRKMEVIR PSSTLTPLVG 
181:	EKHVNGLFGT VVDNFYLVAL ILAMGTSLGL ATPLVTECIQ YLFGIPHTLQ LDAIIISCWI 
241:	LLNAICVAFG LQKGVKIASD VRTYLSFLML GWVFIVGGAS FIVNYFTDSV GTLLMYMPRM 
301:	LFYTDPIGKG GFPQAWTVFY WAWWVIYAIQ MSIFLARISK GRTVRELCLG MVSGLTAGTW 
361:	LIWTILGGNT LQLIDQNILN IPQLIDQYGV PRAIIETWAA LPLSTATMWG FFILCFIATV 
421:	TLINACSYTL AMSTCRSMKE GAEPPLLVRI GWSVLVGIIG IILLALGGLK PIQTAIIAGG 
481:	CPLFFVNIMV TLSFIKDAKV HWKDCSPYTQ KMTH