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2.A.17.1.8
Proton-coupled oligopeptide uptake transporter of 485 aas and 14 TMSs, DtpT or Pot.  Expression of the encoded gene is upregulated upon infection. Transports di- and tripeptides but can not accumulate peptides with a positively charged residue in the C-terminal position.  An aromatic residue patch in the active site of the transporter may be responsible for it's unusual specificity (Sharma et al. 2016).

Accession Number:Q9JXB5
Protein Name:Peptide transporter
Length:485
Molecular Weight:52423.00
Species:Neisseria meningitidis serogroup B (strain MC58) [122586]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate peptides

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSRHPAPTGE KTFFGHPFQL STLFHIELWE RFSFYGMQGI LLIYLYYTAD KGGLGIDKTL 
61:	AGGIVGAYSG SVYLSTILGA WFADRVWGAE KTLFLSGIVV MLGHIVLAAA PGLYGLLIGL 
121:	IFIALGSGGV KSTASSMVGA LYEQDEMRPL RDAGFSIFYI AINIGGFLGP LLTGLLQENI 
181:	GFHYGFGAAA VGMAFGLWRY SLGRKNLPHP TVPHPLSKGQ GKTAAAVGIA LIAALATAIK 
241:	TGLVNLDNFS GILLSTVILA VIAYFARLLT NPRVSSDNKR HIIAYIPLFL TICMFWAVWF 
301:	QIYTVATVYF DETVNRTIGS FTVPVAWKDS MQSLWVILFS GLMAAMWTKM GRKQPKTPLK 
361:	FAMAVFVTGA SFLGFVPFIS SGTPMPIAVF ALIVLAITIG ELMISPIALS ISTKIAPPLF 
421:	KTQMVALNFL AFSLGFTLGG VLFEKGYQAG DEIGFYRLLF YIGAATGFLL LLLVPKLNKM 
481:	LEGTD