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2.A.17.3.16
Nitrate transporter 1.2 (Nitrate transporter NTL1).  Low-affinity proton-dependent nitrate transporter involved in constitutive nitrate uptake but not histidine or dipeptides transport. Involved in (+)-abscisic acid (ABA) transport, but not in gibberellin, indole-3-acetic acid or jasmonic acid import (Kanno et al. 2013).

Accession Number:Q8H157
Protein Name:Nitrate transporter 1.2
Length:585
Molecular Weight:63982.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate nitrate, Abscisic acid

Cross database links:

Genevestigator: Q8H157
eggNOG: COG3104
HEGENOM: HOG000237400
Entrez Gene ID: 843321   
Pfam: PF00854   
KEGG: ath:AT1G69850   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015293 F:symporter activity
GO:0042128 P:nitrate assimilation
GO:0006857 P:oligopeptide transport
GO:0009624 P:response to nematode

References (7)

[1] “Cloning and functional characterization of an Arabidopsis nitrate transporter gene that encodes a constitutive component of low-affinity uptake.”  Huang N.C.et.al.   10449574
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “Regulation of NRT1 and NRT2 gene families of Arabidopsis thaliana: responses to nitrate provision.”  Okamoto M.et.al.   12668777
[5] “Nematode-induced changes of transporter gene expression in Arabidopsis roots.”  Hammes U.Z.et.al.   16478044
[6] “Nitrate transporters and peptide transporters.”  Tsay Y.F.et.al.   17481610
[7] “The Arabidopsis nitrate transporter NRT1.8 functions in nitrate removal from the xylem sap and mediates cadmium tolerance.”  Li J.Y.et.al.   20501909

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEVEEEVSRW EGYADWRNRA AVKGRHGGML AASFVLVVEI LENLAYLANA SNLVLYLREY 
61:	MHMSPSKSAN DVTNFMGTAF LLALLGGFLS DAFFSTFQIF LISASIEFLG LIILTIQART 
121:	PSLMPPSCDS PTCEEVSGSK AAMLFVGLYL VALGVGGIKG SLASHGAEQF DESTPKGRKQ 
181:	RSTFFNYFVF CLACGALVAV TFVVWLEDNK GWEWGFGVST IAIFVSILIF LSGSRFYRNK 
241:	IPCGSPLTTI LKVLLAASVK CCSSGSSSNA VASMSVSPSN HCVSKGKKEV ESQGELEKPR 
301:	QEEALPPRAQ LTNSLKVLNG AADEKPVHRL LECTVQQVED VKIVLKMLPI FACTIMLNCC 
361:	LAQLSTFSVQ QAASMNTKIG SLKIPPASLP IFPVVFIMIL APIYDHLIIP FARKATKTET 
421:	GVTHLQRIGV GLVLSILAMA VAALVEIKRK GVAKDSGLLD SKETLPVTFL WIALQYLFLG 
481:	SADLFTLAGL LEYFFTEAPS SMRSLATSLS WASLAMGYYL SSVIVSIVNS ITGSSGNTPW 
541:	LRGKSINRYK LDYFYWLMCV LSAANFLHYL FWAMRYKYRS TGSRS