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2.A.17.3.2
Histidine or peptide:H+ symporter

Accession Number:P46032
Protein Name:PT2B aka PTR2-B aka NTR1 aka AT2G02040 aka F14H20.11
Length:585
Molecular Weight:64421.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Histidine, peptides, H+

Cross database links:

Genevestigator: P46032
eggNOG: KOG1237
HEGENOM: HBG605267
RefSeq: NP_178313.1   
Entrez Gene ID: 814735   
Pfam: PF00854   
KEGG: ath:AT2G02040   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0000325 C:plant-type vacuole
GO:0005886 C:plasma membrane
GO:0005774 C:vacuolar membrane
GO:0042936 F:dipeptide transporter activity
GO:0015334 F:high affinity oligopeptide transporter acti...
GO:0042937 F:tripeptide transporter activity
GO:0042938 P:dipeptide transport
GO:0015031 P:protein transport
GO:0042939 P:tripeptide transport

References (5)

[1] “Cloning of a second Arabidopsis peptide transport gene.”  Song W.et.al.   8587981
[2] “Cloning of an Arabidopsis histidine transporting protein related to nitrate and peptide transporters.”  Frommer W.B.et.al.   8033999
[3] “Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.”  Lin X.et.al.   10617197
[4] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[5] “Mapping the Arabidopsis organelle proteome.”  Dunkley T.P.J.et.al.   16618929

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGSIEEEARP LIEEGLILQE VKLYAEDGSV DFNGNPPLKE KTGNWKACPF ILGNECCERL 
61:	AYYGIAGNLI TYLTTKLHQG NVSAATNVTT WQGTCYLTPL IGAVLADAYW GRYWTIACFS 
121:	GIYFIGMSAL TLSASVPALK PAECIGDFCP SATPAQYAMF FGGLYLIALG TGGIKPCVSS 
181:	FGADQFDDTD SRERVRKASF FNWFYFSINI GALVSSSLLV WIQENRGWGL GFGIPTVFMG 
241:	LAIASFFFGT PLYRFQKPGG SPITRISQVV VASFRKSSVK VPEDATLLYE TQDKNSAIAG 
301:	SRKIEHTDDC QYLDKAAVIS EEESKSGDYS NSWRLCTVTQ VEELKILIRM FPIWASGIIF 
361:	SAVYAQMSTM FVQQGRAMNC KIGSFQLPPA ALGTFDTASV IIWVPLYDRF IVPLARKFTG 
421:	VDKGFTEIQR MGIGLFVSVL CMAAAAIVEI IRLHMANDLG LVESGAPVPI SVLWQIPQYF 
481:	ILGAAEVFYF IGQLEFFYDQ SPDAMRSLCS ALALLTNALG NYLSSLILTL VTYFTTRNGQ 
541:	EGWISDNLNS GHLDYFFWLL AGLSLVNMAV YFFSAARYKQ KKASS