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2.A.17.3.7
The root dipeptide/tripeptide transporter, PTRI (Komarova et al., 2008). Transport is electrogenic and dependent on protons. Leak currents are inhibited by Phe-Ala when this peptide binds at the active site with high affinity (Hammes et al., 2010).

Accession Number:Q9M390
Protein Name:Peptide transport-like protein
Length:570
Molecular Weight:64034.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate dipeptides, tripeptides

Cross database links:

Genevestigator: Q9M390
eggNOG: KOG1237
HEGENOM: HBG605267
RefSeq: NP_190982.1   
Entrez Gene ID: 824581   
Pfam: PF00854   
KEGG: ath:AT3G54140   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0042936 F:dipeptide transporter activity
GO:0042937 F:tripeptide transporter activity
GO:0042938 P:dipeptide transport
GO:0006807 P:nitrogen compound metabolic process
GO:0015031 P:protein transport
GO:0042939 P:tripeptide transport

References (4)

[1] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “AtPTR1, a plasma membrane peptide transporter expressed during seed germination and in vascular tissue of Arabidopsis.”  Dietrich D.et.al.   15500465
[4] “AtPTR1 and AtPTR5 transport dipeptides in planta.”  Komarova N.Y.et.al.   18753286

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEEKDVYTQD GTVDIHKNPA NKEKTGNWKA CRFILGNECC ERLAYYGMGT NLVNYLESRL 
61:	NQGNATAANN VTNWSGTCYI TPLIGAFIAD AYLGRYWTIA TFVFIYVSGM TLLTLSASVP 
121:	GLKPGNCNAD TCHPNSSQTA VFFVALYMIA LGTGGIKPCV SSFGADQFDE NDENEKIKKS 
181:	SFFNWFYFSI NVGALIAATV LVWIQMNVGW GWGFGVPTVA MVIAVCFFFF GSRFYRLQRP 
241:	GGSPLTRIFQ VIVAAFRKIS VKVPEDKSLL FETADDESNI KGSRKLVHTD NLKFFDKAAV 
301:	ESQSDSIKDG EVNPWRLCSV TQVEELKSII TLLPVWATGI VFATVYSQMS TMFVLQGNTM 
361:	DQHMGKNFEI PSASLSLFDT VSVLFWTPVY DQFIIPLARK FTRNERGFTQ LQRMGIGLVV 
421:	SIFAMITAGV LEVVRLDYVK THNAYDQKQI HMSIFWQIPQ YLLIGCAEVF TFIGQLEFFY 
481:	DQAPDAMRSL CSALSLTTVA LGNYLSTVLV TVVMKITKKN GKPGWIPDNL NRGHLDYFFY 
541:	LLATLSFLNF LVYLWISKRY KYKKAVGRAH