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2.A.17.4.11
Peptide transporter, Pep1, also called CptB, Opt-2 and Pep-2.  It is of 835 aas and 11 TMSs.  It transports di-, tri- and tetra-peptides including phenylalanylmethionylarginylphenylalaninamide (FMRFamide) and N-acetylaspartylglutamate, both neuropeptides found throughout the animal kingdom. In contrast to CptA (TC# 2.A.17.4.3), CptB has low-affinity for its substrates (Fei et al. 1998).

Accession Number:Q21219
Protein Name:Peptide transporter family 1
Length:835
Molecular Weight:94109.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Apical cell membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGYSESRSES VSSKGKTSYG HELETVPLPE KKIYTTWPDM IRHWPKTTLC IVSNEFCERF 
61:	SYYGMRTVLT FYLLNVLKFT DSQSTIFFNG FTVLCYTTPL LGSIVADGYI GKFWTIFSVS 
121:	ILYAIGQVVL ALASTKNFQS SVHPWMDLSG LLIIAFGTGG IKPCVSAFGG DQFELGQERM 
181:	LSLFFSMFYF SINAGSMIST FISPIFRSQP CLGQDSCYPM AFGIPAILMI VATLVFMGGS 
241:	FWYKKNPPKD NVFGEVSRLM FRAVGNKMKS GSTPKEHWLL HYLTTHDCAL DAKCLELQAE 
301:	KRNKNLCQKK KFIDDVRSLL RVLVMFLPVP MFWALYDQQG SVWLIQAIQM DCRLSDTLLL 
361:	LPDQMQTLNA VLILLFIPLF QVIIYPVAAK CVRLTPLRKM VTGGLLASLA FLITGFVQLQ 
421:	VNTTLPTLPE EGEASISFWN QFETDCTITV MSGIHKRVLP HDKYLHEDKK NKSGIYNLFT 
481:	TKSPAKGNGD WTLTYDLSYD GACGDTSKLE KTVKVTAKSK KIIYVGVGSF GYYQNTANTD 
541:	KPTDGTGEFS MGIVTVFNSS YGGNFAMCRQ NTSDFDVNHP CNPRHPADFY FWETDYNSHT 
601:	DDRDQNATIT GSLSSQPAVT YKQKSVKPGY WQLYYLLNTP KDVDRQTYNK TATLVAPTNY 
661:	GFHRVKQGGV FIYALTGTYE NPKIHELQIV QSNSVSILWQ IPQIVVITAA EILFSITGYE 
721:	FAYSQSAPSM KALVQALWLL TTAAGDSIIV VITILNLFEN MAVEFFVYAA AMFVVIAIFA 
781:	LLSIFYYTYN YYTTDEEDGE IGVDDEEEIE DHNPRYSIDN KGFHPDEKDT FDMHF