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2.A.17.4.6
Oligopeptide transporter, PepT1 (Slc15A1b) (Bucking and Schulte, 2012) (expressed in freshwater acclimated fish)

Accession Number:H2DJV9
Protein Name:Oligopeptide transporter PEPT1
Length:722
Molecular Weight:80682.00
Species:Fundulus heteroclitus macrolepidotus [351661]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate peptides

Cross database links:

Pfam: PF00854   

Gene Ontology

GO:0016020 C:membrane
GO:0005215 F:transporter activity
GO:0006857 P:oligopeptide transport

References (1)

[1] “Environmental and nutritional regulation of expression and function of two peptide transporter (PepT1) isoforms in a euryhaline teleost.”  Bucking C.et.al.   22227314

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKSKKRSVTV CGYPLSIFFI VVNEFCERFS YYGMRAVLVL YFKYFLKWDD DFSTTIYHTF 
61:	VALCYLSPIL GAIVADSWLG KFKTIVYLSV VYAAGQVVMA VSAIHDITDG NKDGTPDNMA 
121:	LHIALSMVGL LLIALGTGGI KPCVAAFGGD QFSEDQEKQR STFFSIFYLS INAGSLLSTV 
181:	ITPILRAQKC GIHTKQQCYP LAFGVPAALM VVALIVFILG SSMYNKTAPS GNIMVKVCKC 
241:	IFFAIKNRFR HRSSAYPKRE HWMDWAEEKY DKLLIAQVKM VLKVLFLYIP LPMFWALFDQ 
301:	QGSRWTLRAT TMDGNFGLMV IQPDQMQTVN PILILIMVPV VDFIIYPLIS KCKLNFTPLR 
361:	KMTGGMFLAA LAFVAAALVQ LQIDATLPTF PSSNEQQAKF INMVNRNLSI ADGRENFHLG 
421:	AFEGRQDYLT YTEPFLLTIN SGSPNLISLP DGTRNTIVIV EQGPAFGYIT FQDIVAKPEE 
481:	GANAIRFFNG YGSVLNITVG DQEYGDIVPN NMSIFINVPQ GTGKFFMKNN GGVECVFSRK 
541:	FGFGSSYTFL IPPTFVFGEH CGESIKEVEN IKPNSIHMAW QIPQYFLMTS GEVFFSVTGL 
601:	EFSYSQAPSN MKSVLQAGWL LTVAVGNIIV LIVAEAATLP DQWAEYILFS SLLVLVCIIF 
661:	AIMAYFYTYT DPAKIEALFA NPEPDDKEKK NLEMTKKDMA EKHERRSSDT SSDEEDGKQT 
721:	NF