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2.A.18.2.3
General amino acid transporter 3, AAP3 (transports all neutral, acidic and basic amino acids tested)

Accession Number:Q39134
Protein Name:AAP3 aka F2P24.9 aka AT1G77380
Length:476
Molecular Weight:52037.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1
Substrate Amino acids

Cross database links:

eggNOG: KOG1303
HEGENOM: HBG319901
RefSeq: NP_177862.1   
Entrez Gene ID: 844074   
Pfam: PF01490   
KEGG: ath:AT1G77380   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0031965 C:nuclear membrane
GO:0005886 C:plasma membrane
GO:0015293 F:symporter activity
GO:0015802 P:basic amino acid transport

References (7)

[1] “Substrate specificity and expression profile of amino acid transporters (AAPs) in Arabidopsis.”  Fischer W.-N.et.al.   7608199
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “Identification and characterization of GABA, proline and quaternary ammonium compound transporters from Arabidopsis thaliana.”  Breitkreuz K.E.et.al.   10359089
[5] “Low and high affinity amino acid H+-cotransporters for cellular import of neutral and charged amino acids.”  Fischer W.-N.et.al.   12148530
[6] “Root phloem-specific expression of the plasma membrane amino acid proton co-transporter AAP3.”  Okumoto S.et.al.   15361541
[7] “Root uptake of cationic amino acids by Arabidopsis depends on functional expression of amino acid permease 5.”  Svennerstam H.et.al.   18681934

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MVQNHQTVLA VDMPQTGGSK YLDDDGKNKR TGSVWTASAH IITAVIGSGV LSLAWATAQL 
61:	GWLAGPVVML LFSAVTYFTS SLLAACYRSG DPISGKRNYT YMDAVRSNLG GVKVTLCGIV 
121:	QYLNIFGVAI GYTIASAISM MAIKRSNCFH KSGGKDPCHM NSNPYMIAFG LVQILFSQIP 
181:	DFDQLWWLSI LAAVMSFTYS SAGLALGIAQ VVVNGKVKGS LTGISIGAVT ETQKIWRTFQ 
241:	ALGDIAFAYS YSIILIEIQD TVKSPPSEEK TMKKATLVSV SVTTMFYMLC GCMGYAAFGD 
301:	LSPGNLLTGF GFYNPYWLLD IANAAIVIHL IGAYQVYCQP LFAFIEKQAS IQFPDSEFIA 
361:	KDIKIPIPGF KPLRLNVFRL IWRTVFVIIT TVISMLLPFF NDVVGLLGAL GFWPLTVYFP 
421:	VEMYIAQKKI PRWSTRWVCL QVFSLGCLVV SIAAAAGSIA GVLLDLKSYK PFRSEY