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2.A.18.6.10
Vacuolar broad specificity amino acid transporter 5 Avt5. Transports histidine, gluatmate, tyrosine, arginine, lysine and serine (Chardwiriyapreecha et al., 2010).

Accession Number:P38176
Protein Name:Vacuolar amino acid transporter 5
Length:459
Molecular Weight:50892.00
Species:saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Amino acids

Cross database links:

Genevestigator: P38176
eggNOG: fuNOG04087
HEGENOM: HBG332582
DIP: DIP-2846N
RefSeq: NP_009464.2   
Entrez Gene ID: 852189   
Pfam: PF01490   
KEGG: sce:YBL089W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005774 C:vacuolar membrane
GO:0006865 P:amino acid transport

References (4)

[1] “Sequence analysis of a 78.6 kb segment of the left end of Saccharomyces cerevisiae chromosome II.”  Obermaier B.et.al.   7502586
[2] “Complete DNA sequence of yeast chromosome II.”  Feldmann H.et.al.   7813418
[3] “A family of yeast proteins mediating bidirectional vacuolar amino acid transport.”  Russnak R.et.al.   11274162
[4] “Sequencing and comparison of yeast species to identify genes and regulatory elements.”  Kellis M.et.al.   12748633

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPSNVRSGVL TLLHTACGAG VLAMPFAFKP FGLMPGLITL TFCGICSLCG LLLQTRIAKY 
61:	VPKSENASFA KLTQLINPSI SVVFDFAIAV KCFGVGVSYL IIVGDLVPQI VQSIFYRNDD 
121:	NMSGSQEHHM FLDRRLYITL IIVFVISPLC FKRSLNSLRY ASMIAIVSVA YLSGLIIYHF 
181:	VNRHQLERGQ VYFMVPHGDS QSHSPLTTLP IFVFAYTCHH NMFSVINEQV DKSFKVIRRI 
241:	PIFAIVLAYF LYIIIGGTGY MTFGENIVGN ILTLYPNSIS TTIGRLAMLL LVMLAFPLQC 
301:	HPCRSSVKNI IIFIENFRKG KLYDNRASFI PLDNFNSEDP QEAPTQQNNE EPNLRSESLR 
361:	HINIITLCIL LFSYLLAISI TSLAKVLAIV GATGSTSISF ILPGLFGYKL IGSEFTGTNE 
421:	RVPTSIKIFK YLSLSLFIWG IAVMVASLSA IVFLGTSSH