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2.A.18.6.16
Sodium-coupled amino acid transporter 10, SNAT10.  Expressed in several endocrine organs (Sundberg et al. 2008). Transports glutamine, glutamate and aspartate in neuronal and astrocytic cells (Hellsten et al. 2017).

Accession Number:Q9HBR0
Protein Name:Putative sodium-coupled neutral amino acid transporter 10
Length:1119
Molecular Weight:119762.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Amino acids

Cross database links:

Genevestigator: Q9HBR0
eggNOG: COG0814
HEGENOM: HOG000154237
Entrez Gene ID: 124565   
Pfam: PF01490   
KEGG: hsa:124565   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0006865 P:amino acid transport
GO:0006814 P:sodium ion transport

References (4)

[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[2] “DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.”  Zody M.C.et.al.   16625196
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Large-scale cDNA transfection screening for genes related to cancer development and progression.”  Wan D.et.al.   15498874

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTAAAASNWG LITNIVNSIV GVSVLTMPFC FKQCGIVLGA LLLVFCSWMT HQSCMFLVKS 
61:	ASLSKRRTYA GLAFHAYGKA GKMLVETSMI GLMLGTCIAF YVVIGDLGSN FFARLFGFQV 
121:	GGTFRMFLLF AVSLCIVLPL SLQRNMMASI QSFSAMALLF YTVFMFVIVL SSLKHGLFSG 
181:	QWLRRVSYVR WEGVFRCIPI FGMSFACQSQ VLPTYDSLDE PSVKTMSSIF ASSLNVVTTF 
241:	YVMVGFFGYV SFTEATAGNV LMHFPSNLVT EMLRVGFMMS VAVGFPMMIL PCRQALSTLL 
301:	CEQQQKDGTF AAGGYMPPLR FKALTLSVVF GTMVGGILIP NVETILGLTG ATMGSLICFI 
361:	CPALIYKKIH KNALSSQVVL WVGLGVLVVS TVTTLSVSEE VPEDLAEEAP GGRLGEAEGL 
421:	MKVEAARLSA QDPVVAVAED GREKPKLPKE REELEQAQIK GPVDVPGRED GKEAPEEAQL 
481:	DRPGQGIAVP VGEAHRHEPP VPHDKVVVDE GQDREVPEEN KPPSRHAGGK APGVQGQMAP 
541:	PLPDSEREKQ EPEQGEVGKR PGQAQALEEA GDLPEDPQKV PEADGQPAVQ PAKEDLGPGD 
601:	RGLHPRPQAV LSEQQNGLAV GGGEKAKGGP PPGNAAGDTG QPAEDSDHGG KPPLPAEKPA 
661:	PGPGLPPEPR EQRDVERAGG NQAASQLEEA GRAEMLDHAV LLQVIKEQQV QQKRLLDQQE 
721:	KLLAVIEEQH KEIHQQRQED EEDKPRQVEV HQEPGAAVPR GQEAPEGKAR ETVENLPPLP 
781:	LDPVLRAPGG RPAPSQDLNQ RSLEHSEGPV GRDPAGPPDG GPDTEPRAAQ AKLRDGQKDA 
841:	APRAAGTVKE LPKGPEQVPV PDPAREAGGP EERLAEEFPG QSQDVTGGSQ DRKKPGKEVA 
901:	ATGTSILKEA NWLVAGPGAE TGDPRMKPKQ VSRDLGLAAD LPGGAEGAAA QPQAVLRQPE 
961:	LRVISDGEQG GQQGHRLDHG GHLEMRKARG GDHVPVSHEQ PRGGEDAAVQ EPRQRPEPEL 
1021:	GLKRAVPGGQ RPDNAKPNRD LKLQAGSDLR RRRRDLGPHA EGQLAPRDGV IIGLNPLPDV 
1081:	QVNDLRGALD AQLRQAAGGA LQVVHSRQLR QAPGPPEES