TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.18.6.19
Vacuolar amino acid transporter 7

Accession Number:P40501
Protein Name:Vacuolar amino acid transporter 7
Length:490
Molecular Weight:53737.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Amino acids

Cross database links:

Genevestigator: P40501
eggNOG: COG0814
HEGENOM: HOG000173527
DIP: DIP-7299N
Entrez Gene ID: 854721   
Pfam: PF01490   
KEGG: sce:YIL088C   

Gene Ontology

GO:0000324 C:fungal-type vacuole
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005774 C:vacuolar membrane
GO:0015171 F:amino acid transmembrane transporter activity

References (4)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.”  Churcher C.M.et.al.   9169870
[2] “A family of yeast proteins mediating bidirectional vacuolar amino acid transport.”  Russnak R.et.al.   11274162
[3] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[4] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MEATSSALSS TANLVKTIVG AGTLAIPYSF KSDGVLVGVI LTLLAAVTSG LGLFVLSKCS 
61:	KTLINPRNSS FFTLCMLTYP TLAPIFDLAM IVQCFGVGLS YLVLIGDLFP GLFGGERNYW 
121:	IIASAVIIIP LCLVKKLDQL KYSSILGLFA LAYISILVFS HFVFELGKGE LTNILRNDIC 
181:	WWKIHDFKGL LSTFSIIIFA FTGSMNLFPM INELKDNSME NITFVINNSI SLSTALFLIV 
241:	GLSGYLTFGN ETLGNLMLNY DPNSIWIVIG KFCLGSMLIL SFPLLFHPLR IAVNNVIIWI 
301:	EITYGGANPE EDPQVSEYTR ASNLRPISMT VEDPAQPSDA LDATSYNEQE CLLPNGNFDN 
361:	GSIESQENNN DERGTMAVAG DNEHHAPFVK SRFYWITALL LISMYTLALS VQSFALVLSF 
421:	VGATGSTSIS FTLPGLLGYK LIGLDSLAIG KMIPPKDRFY KRCSLLLVFY GLSVMFLSLY 
481:	VTVFNRSDEA