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2.A.18.6.9
Arginine-specific transporter, AAP3 (KM (Arg) = 2μM)

Accession Number:Q86G79
Protein Name:Arginine transporter AAP3
Length:480
Molecular Weight:52418.00
Species:Leishmania donovani [5661]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Arginine

Cross database links:

Pfam: PF01490   

Gene Ontology

GO:0016021 C:integral to membrane

References (2)

[1] “Novel motifs in amino acid permease genes from Leishmania.”  Akerman M.et.al.   15522240
[2] “A novel high-affinity arginine transporter from the human parasitic protozoan Leishmania donovani.”  Shaked-Mishan P.et.al.   16556218

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MSKPSKSIPA QAEGEVLSDS LIDGNPGNAV DKHPSGEQGN HLHKNGSLTA SSSHNENGAD 
61:	AAKPGRNIIF RFTGWLIPYG GVISNCFSLG SVTLGGGIIS MPSSFAMSGI IMSVIYLVVI 
121:	TAATVYTMTL LGYAMKATGC KTFEELSLVL FGRGWDYFVG FVLWLSCFGT AVAYISAVSS 
181:	LITPILEKSP GTPAYLLTTS GNRLITSLIW LVFMVPVVIP KRVNSIRYVS AIGVFMVLYF 
241:	AVTIVVHSSM NGLKEGMRGD MKYFTSGNEA VYGLSIFIFS FLCQAVTGSV YFEQRPRPSV 
301:	RQLTIASAIS MTVCMVLYIF TGVFGYFDFA DDTQDSILYN FDPVHQPYMM IAYIGMLIKI 
361:	CAAFAMNMLP CRNFAYHCLN WDLETVPYWK HTIAILTMAV ATLVCGLFIP SINTAFGLVG 
421:	SLCGGFIGFI FPAYFWMYSG NWSLSSVGIW HWLATYFLVV AGVIAVVFGT ISTIYYSFFV