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2.A.18.7.4
Proline/alanine transporter of 488 aas and 10 TMSs, AAP24. The first 18 amino acids of the negatively charged N-terminal LdAAP24 tail are required for alanine transport and may facilitate the electrostatic interactions of the entire negatively charged N-terminal tail with the positively charged internal loops in the transmembrane domain.  This mechanism may underlie regulation of substrate flux rate for this and other transporters (Schlisselberg et al. 2015).

Accession Number:A4HUI4
Protein Name:Putative amino acid transporter
Length:488
Molecular Weight:53982.00
Species:Leishmania infantum [5671]
Number of TMSs:10
Substrate Proline, Alanine

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FASTA formatted sequence
1:	MSRLPSTASD NEPAHLTQME DERYRETLIE GFMSVPEVEG DEGASNGDPS CQQKDQKAQE 
61:	YVEMDDDDDM TVVRLAAGEL KENTNICKSA FHVFKANVGT GVFLLPTFYP DAGYVVSVIL 
121:	GVLIGAAVVD CTRLLVDVKI KINRSDVTTY SQVCRYVCGA GLGWFLFVAM CLAQFGFCLM 
181:	YTQLFGDTMV ELANFKGSKY LWVSVVFFLC FPMTCFSDNL SLLAITSIIA TVSVFYSLIC 
241:	CFAMSLMQLS QDGVHPSCDV AGNRIPVGWF NNLANNMMVL EGIAIILPVH AACTQKRLVP 
301:	KMATLVITGV IAWYILFGLT GYLAYGNSMT TSLVAKMAHS SWGTSVRVFF MLNLVFTYPV 
361:	QFMSAMQLID QTVRCKPRSW MGIGLRLLIN LVIWALAMGM PTSAVNTVVA FVGALPSVCM 
421:	VMIIPSILAM HVKYAVEHPD ADRNTLQYWK KIFVTAPCFT FKRIRCYVYL VVAVLIMVIG 
481:	TYSIAETL