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2.A.19.2.10
Vacuolar cation/proton exchanger 1a (Ca(2+)/H(+) exchanger 1a) (OsCAX1a)

Accession Number:Q769E5
Protein Name:Vacuolar cation/proton exchanger 1a
Length:451
Molecular Weight:47707.00
Species:Oryza sativa subsp. japonica (Rice) [39947]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Ca2+, H+

Cross database links:

eggNOG: COG0387
HEGENOM: HOG000083011
Entrez Gene ID: 4324573   
Pfam: PF01699   
KEGG: osa:4324573   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005774 C:vacuolar membrane
GO:0015297 F:antiporter activity
GO:0008324 F:cation transmembrane transporter activity
GO:0006816 P:calcium ion transport

References (3)

[1] “Residues in internal repeats of the rice cation/H+ exchanger are involved in the transport and selection of cations.”  Kamiya T.et.al.   14561741
[2] “The genome sequence and structure of rice chromosome 1.”  Sasaki T.et.al.   12447438
[3] “Expression profile of the genes for rice cation/h+ exchanger family and functional analysis in yeast.”  Kamiya T.et.al.   16043430

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MEAAAAMEAG RKLAARHPHG RSRTAHNMSS SSLRKKSDAA LVRKVPVAPL RPLLANLQEV 
61:	FLATKLAVLF PAVPLAIAAQ CFRFDQVWVF ALSLLGLIPL AERVSFLTEQ IALYTGPTVG 
121:	GLLNATCGNA TELIIALFAL LKGKIEVVKC SLLGSVLSNL LLVLGTSLFC GGVVNLGARQ 
181:	PYDRNQSDVS TALLFLAVLC HSAPLLLRYA VAAGEHSVSA TSAAASLDLS RACSFVMLAS 
241:	YVAYLFFQLK THRQLFEPQE VDGGDAGDDD EEPALGFASA LFWLALMTAV ISVLSEYVVG 
301:	TIEPTSQSWG LSVSFISIIL LPIVGNAAEH AGAIIFALKN KLDITLGVAL GSATQISMFV 
361:	VPLSVLVAWI MGVQMDLDFK LLETGSLFMA VLVTAFTLQD GTSHYLKGIL LLLCYIVIGA 
421:	CFFVARQPAG HANSNGALLD VPTGSMSVQA A