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2.A.19.4.3
The sea urchin spermatozoan flagellar K+-dependent Ca2+:Na+ antiporter SuNCKX (Ca2+ + K+:4 Na+ antiporter)

Accession Number:Q8T8P0
Protein Name:SuNCKX
Length:652
Molecular Weight:71962.00
Species:Strongylocentrotus purpuratus (Purple sea urchin) [7668]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Ca2+, K+, Na+

Cross database links:

RefSeq: NP_999790.1   
Entrez Gene ID: 373483   
Pfam: PF01699   
KEGG: spu:373483   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0055085 P:transmembrane transport

References (1)

[1] “A flagellar K(+)-dependent Na(+)/Ca(2+) exchanger keeps Ca(2+) low in sea urchin spermatozoa.”  Su Y.H.et.al.   12011436

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MQSHEIAVQS EPVRRTGRLR KPPWRHRVGL GGRDKSKIGT LNKQWLSRTS IVVAFFLISS 
61:	ILYITSNRAS DMQDKYQSDG NMGRSLLSNE SGGHVRPPWE TCSFESANQP VLWVIFYAIF 
121:	VIILFIAIAI ICDDFFVPSL EVISETLSLS EDVAGATFMA AGSSAPELFT AVIGVAFESD 
181:	VGVGTIVGSA VFNILIIIAL TAALAGQVLN LDWRPLARDS FFYGLSLVCF IVFSWDTEFT 
241:	WWESLILVIL YVIYLILMKV NPIIMDKTKH ITCGGFCRNE VAPLDAEAGE AVGETAVQTV 
301:	TDGPENPGQN GTANGNALPR KLPPLQAHEL SEENRKISVL SNQSLAVPGN NHIFHHVKHG 
361:	ELSSNFRRQS LVDGLNHPHH HHHHHDEHDG DHKPHAQGEK EEEEDKKSED SEEEPTLRPL 
421:	PCLPAINMYY PDKEILESTC GCLRYSLKWL LFVISFPFMC AFSWTIPNCS VPRLRKWYVA 
481:	SFLLSIFWIA ALSFGMVTLV VKIGCILNIS DYTMGLVIVA VGTSVPDALS SILVARDGYG 
541:	DMAVSNAIGS NVFDINLGIG LPYLIRIAIN GGTNIALLNP ADQLRFDDGA FGPIPPHAKF 
601:	GFILLLILLF TIFAFTAVRF RLNAVIGVSF AIMYVLFMVY AFVQEIVCDG GC