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2.A.19.5.2
Cation (Ca2+/Na+):proton antiporter, ChaA or CaxA (confers both Na+ and Ca2+ resistance) (Wei et al., 2007)

Accession Number:Q0ZAI3
Protein Name:ChaA
Length:319
Molecular Weight:33652.00
Species:Alkalimonas amylolytica [152573]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Ca2+, Na+, H+

Cross database links:

Pfam: PF01699   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0055085 P:transmembrane transport

References (1)

[1] “Three putative cation/proton antiporters from the soda lake alkaliphile Alkalimonas amylolytica N10 complement an alkali-sensitive Escherichia coli mutant.”  Wei Y.et.al.   17600061

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MLVATIFVLV GLVLLIWSAD RFVYGASSIA RNLNISPMII GLTIVAMGSS APEIMVSATA 
61:	AWQGRLDTAV GNALGSNITN ILLVIGATAL LKPIAVASMT IKREFPLLIL VTLLGYLFLA 
121:	DQSLTRAEGA LFLGGFVLFL VLMVYWGKHA PPDDPLLTEY QAELPPPTPT WQATVWLVLG 
181:	LALLLASSQL LVHGAVTIAS HFGMSDLLIG LTIIAIGTSL PELAASLIGI LKGEDDLALG 
241:	NIIGSNIFNI LAVLGVGTII APGVIDAAAA GRDSYVMMAA TLALLLMSLR LGKLRRINRV 
301:	EGCILLMAFI GYQYLLFSS