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2.A.2.4.1
Sucrose:H+ symporter, Suc1 (provides osmotic driving force for anther dehiscence, pollen germination and pollen tube growth; also transports other glucosides such as maltose and phenylglucosides. Km (sucrose)= 0.5 mM. (Stadler et al., 1999)).  In wheat (Triticum aesticum), there are at least three isoforms designated Sut2A, Sut2B and Sut2D (Deol et al. 2013).

Accession Number:Q39232
Protein Name:SucL aka SUC1 aka F17M19.3
Length:513
Molecular Weight:54858.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Sucrose

Cross database links:

Genevestigator: Q39232
HEGENOM: HBG587870
RefSeq: NP_177333.1   
Entrez Gene ID: 843519   
Pfam: PF00083   
KEGG: ath:AT1G71880   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0005773 C:vacuole
GO:0008506 F:sucrose:hydrogen symporter activity
GO:0009846 P:pollen germination
GO:0009624 P:response to nematode
GO:0015770 P:sucrose transport

References (9)

[1] “SUC1 and SUC2: two sucrose transporters from Arabidopsis thaliana; expression and characterization in baker's yeast and identification of the histidine-tagged protein.”  Sauer N.et.al.   7920705
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “A kinetic model with ordered cytoplasmic dissociation for SUC1, an Arabidopsis H(+)/sucrose cotransporter expressed in Xenopus oocytes.”  Zhou J.-J.et.al.   9307438
[5] “His-65 in the proton-sucrose symporter is an essential amino acid whose modification with site-directed mutagenesis increases transport activity.”  Lu J.M.-Y.et.al.   9671798
[6] “The AtSUC1 sucrose carrier may represent the osmotic driving force for anther dehiscence and pollen tube growth in Arabidopsis.”  Stadler R.et.al.   10476074
[7] “Sugar-induced increase in cytosolic Ca(2+) in Arabidopsis thaliana whole plants.”  Furuichi T.et.al.   11673631
[8] “Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.”  Shimaoka T.et.al.   15215502
[9] “Temporal analysis of sucrose-induced phosphorylation changes in plasma membrane proteins of Arabidopsis.”  Niittylae T.et.al.   17586839

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGAYETEKPT KDAAALETQS PEDFDQPSPL RKIISVASIA AGVQFGWALQ LSLLTPYVQL 
61:	LGIPHKWSSL IWLCGPVSGM IVQPIVGFHS DRCRSKFGRR RPFIATGAAL VAVAVFLIGY 
121:	AADFGYKMGD KLEEKVKVRA IGIFALGFWI LDVANNTLQG PCRAFLADLA AGDAKRTRVA 
181:	NAFFSFFMAV GNVLGYAAGS YTNLHKMFPF TMTKACDIYC ANLKTCFFLS ITLLLIVTVT 
241:	SLWYVNDKQW SPPPRNADDD EKTSSVPLFG EIFGAFKVMK RPMWMLLIVT ALNWIAWFPF 
301:	LLFDTDWMGR EVFGGDSDGN ERSKKLYSLG VQSGAMGLMF NSIVLGFMSL GVEWIGRKLG 
361:	GAKRLWGIVN FILAAGLAMT VLVTKFAEDH RKTAGDLAGP SASVKAGALS LFAVLGIPLA 
421:	ITFSTPFALA SIFSSCSGAG QGLSLGVLNL AIVIPQMIVS LGGGPFDALF GGGNLPAFIV 
481:	AAIAAAISGV LALTVLPSPP PDAPKATTMG GFH