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2.A.2.4.10
Proton:glucose symporter A; proton-associated sugar transporter A  (PAST-A) (present in brain and deleted in neuroblastoma 5 (DNb-5).  Solute carrier family 45 member 1, SLC45A1 (Bartölke et al. 2014).

Accession Number:Q9Y2W3
Protein Name:Proton-associated sugar transporter A
Length:748
Molecular Weight:80843.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate glucose

Cross database links:

Genevestigator: Q9Y2W3
eggNOG: NOG317436
HEGENOM: HOG000231090
Entrez Gene ID: 50651   
Pfam: PF07690   
KEGG: hsa:50651   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005355 F:glucose transmembrane transporter activity
GO:0015293 F:symporter activity

References (2)

[1] “The DNA sequence and biological annotation of human chromosome 1.”  Gregory S.G.et.al.   16710414
[2] “Identification and characterization of novel genes located at the t(1;15)(p36.2;q24) translocation breakpoint in the neuroblastoma cell line NGP.”  Amler L.C.et.al.   10729226

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MIPAASSTPP GDALFPSVAP QDFWRSQVTG YSGSVTRHLS HRANNFKRHP KRRKCIRPSP 
61:	PPPPNTPCPL ELVDFGDLHP QRSFRELLFN GCILFGIEFS YAMETAYVTP VLLQMGLPDQ 
121:	LYSLVWFISP ILGFLLQPLL GAWSDRCTSR FGRRRPFILV LAIGALLGLS LLLNGRDIGI 
181:	ALADVTGNHK WGLLLTVCGV VLMDFSADSA DNPSHAYMMD VCSPADQDRG LNIHALLAGL 
241:	GGGFGYVVGG IHWDKTGFGR ALGGQLRVIY LFTAVTLSVT TVLTLVSIPE RPLRPPSEKR 
301:	AAMKSPSLPL PPSPPVLPEE GPGDSLPSHT ATNFSSPISP PSPLTPKYGS FISRDSSLTG 
361:	ISEFASSFGT ANIDSVLIDC FTGGHDSYLA IPGSVPRPPI SVSFPRAPDG FYRQDRGLLE 
421:	GREGALTSGC DGDILRVGSL DTSKPRSSGI LKRPQTLAIP DAAGGGGPET SRRRNVTFSQ 
481:	QVANILLNGV KYESELTGSS ERAEQPLSVG RLCSTICNMP KALRTLCVNH FLGWLSFEGM 
541:	LLFYTDFMGE VVFQGDPKAP HTSEAYQKYN SGVTMGCWGM CIYAFSAAFY SAILEKLEEF 
601:	LSVRTLYFIA YLAFGLGTGL ATLSRNLYVV LSLCITYGIL FSTLCTLPYS LLCDYYQSKK 
661:	FAGSSADGTR RGMGVDISLL SCQYFLAQIL VSLVLGPLTS AVGSANGVMY FSSLVSFLGC 
721:	LYSSLFVIYE IPPSDAADEE HRPLLLNV